Orthogonal Strategies: Immunohistochemistry-Paraffin: VPS26A Antibody (CL2287) [NBP2-36754] - Staining in human testis and skeletal muscle tissues. Corresponding VPS26A RNA-seq data are presented for the same ...read more
Genetic Strategies: Western Blot: VPS26A Antibody (CL2287) [NBP2-36754] - Analysis of extracts from U-251 cells, transfected with: control siRNA, target specific siRNA probe #1, target specific siRNA probe #2, ...read more
Immunocytochemistry/ Immunofluorescence: VPS26A Antibody (CL2287) [NBP2-36754] - Staining in U251 cell line showing distinct staining of endosomes in green. Microtubule-staining and nuclear probes are visualized in red ...read more
Western Blot: VPS26A Antibody (CL2287) [NBP2-36754] - Lane 1: Marker [kDa]. Lane 2: Human cell line U-251 MG
Immunocytochemistry/ Immunofluorescence: VPS26A Antibody (CL2287) [NBP2-36754] - Staining in HeLa cell line showing distinct staining of endosomes in green. Microtubule-staining and nuclear probes are visualized in red ...read more
Immunocytochemistry/ Immunofluorescence: VPS26A Antibody (CL2287) [NBP2-36754] - Staining of human cell line A431 showing distinct staining of endosomes in green. Microtubule-staining and nuclear probes are visualized ...read more
Immunocytochemistry/ Immunofluorescence: VPS26A Antibody (CL2287) [NBP2-36754] - Staining in MCF7 cell line showing distinct staining of endosomes in green. Microtubule-staining and nuclear probes are visualized in red ...read more
Immunocytochemistry/ Immunofluorescence: VPS26A Antibody (CL2287) [NBP2-36754] - Staining in U2OS cell line with Anti-VSP26A monoclonal antibody, showing distinct staining of endosomes in green. Microtubule- and nuclear ...read more
Immunohistochemistry-Paraffin: VPS26A Antibody (CL2287) [NBP2-36754] - Staining of human testis shows moderate to strong cytoplasmic positivity in cells in seminiferous ducts.
Immunohistochemistry-Paraffin: VPS26A Antibody (CL2287) [NBP2-36754] - Staining of human fallopian tube shows moderate to strong cytoplasmic positivity in glandular cells.
Immunohistochemistry-Paraffin: VPS26A Antibody (CL2287) [NBP2-36754] - Staining of human duodenum shows moderate to strong cytoplasmic positivity in glandular cells.
Immunohistochemistry-Paraffin: VPS26A Antibody (CL2287) [NBP2-36754] - Staining of human skeletal muscle shows no positivity in striated muscle fibers as expected.
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.2) and 40% Glycerol
Preservative
0.02% Sodium Azide
Purity
Protein A purified
Alternate Names for VPS26A Antibody (CL2287)
FLJ12930
HB58
Hbeta58
hVPS26
PEP8A
vacuolar protein sorting 26 (yeast homolog)
vacuolar protein sorting 26 homolog A (S. pombe)
vacuolar protein sorting 26 homolog A (yeast)
vacuolar protein sorting-associated protein 26A
Vesicle protein sorting 26A
VPS26vacuolar protein sorting 26 (yeast)
Background
VPS26 belongs to a group of vacuolar protein sorting (VPS) genes. The encoded protein is a component of a large multimeric complex, termed the retromer complex, involved in retrograde transport of proteins from endosomes to the trans-Golgi network. The close structural similarity between the yeast and human proteins that make up this complex suggests a similarity in function. Expression studies in yeast and mammalian cells indicate that this protein interacts directly with VPS35, which serves as the core of the retromer complex.
Limitations
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
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