Viperin Antibody

Viperin is a 43kDa protein which is one of several hundred interferon inducible viral proteins. Elevated expression of viperin is induced by LPS and poly I:C through TLR dependent signaling pathways. Sendai virus mediated viperin expression is induced independently of TLR signaling pathways through RLRs - RIG-I and MAVs (Severa, 2006). Viperin has been shown to play an important role in interferon mediated anti-viral activity in a Hepatitis C virus model system (Helbig, 2011). Viperin is induced in lymphoid cells and dendritic cells (DCs) and highly induced in neutrophils and macrophages during acute LCMV infection in mice (Hinson, ). Viperin functions as a mediator of viral resistance and as a marker for interferon responsiveness making its detection and mechanism of action through specific antibody probes valuable for further studies. Additionally, viperin antibodies provide useful information for analysis of specific cell types responsive to interferon making it valuable for phenotyping studies complementing mechanism of action analysis.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

We have publications tested in 1 confirmed species: Mouse.

We have publications tested in 1 application: WB.

Showing Publication 1 - 1 of 1.

Publication using NBP2-03971	Applications	Species
Feriotti C, SA-Pessoa J, CalderOn-GonzAlez R et al. Klebsiella pneumoniae hijacks the Toll-IL-1R protein SARM1 in a type I IFN-dependent manner to antagonize host immunity Cell reports 2022-08-09 [PMID: 35947948] (WB, Mouse) Details: Dilutions: 1:1000	WB	Mouse

Array NBP2-03971

• Viperin Antibodies
• Viperin ELISA Kits
• Viperin Lysate
• Viperin Proteins