ULBP-2 Antibody (MM0593-7F33) [CoraFluor™ 1]

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications Flow, B/N
Clone
MM0593-7F33
Clonality
Monoclonal
Host
Mouse
Conjugate
CoraFluor 1

Order Details

ULBP-2 Antibody (MM0593-7F33) [CoraFluor™ 1] Summary

Description
CoraFluor(TM) 1 is a high performance terbium-based TR-FRET (Time-Resolved Fluorescence Resonance Energy Transfer) or TRF (Time-Resolved Fluorescence) donor for high throughput assay development. CoraFluor(IM) 1 absorbs UV light at approximately 340 nm, and emits at approximately 490 nm, 545 nm, 585 nm and 620 nm. It is compatible with common acceptor dyes that absorb at the emission wavelengths of CoraFluor(TM) 1. CoraFluor(TM) 1 can be used for the development of robust and scalable TR-FRET binding assays such as target engagement, ternary complex, protein-protein interaction and protein quantification assays.
Immunogen
Human recombinant ULBP-2
Isotype
IgG2
Clonality
Monoclonal
Host
Mouse
Gene
ULBP2
Purity
Protein G purified
Innovator's Reward
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Applications/Dilutions

Dilutions
  • Block/Neutralize
  • Flow Cytometry
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark. Do not freeze.
Buffer
PBS
Preservative
No Preservative
Purity
Protein G purified

Notes

CoraFluor (TM) is a trademark of Bio-Techne Corp. Sold for research purposes only under agreement from Massachusetts General Hospital. US patent 2022/0025254

Alternate Names for ULBP-2 Antibody (MM0593-7F33) [CoraFluor™ 1]

  • ALCAN-alpha
  • N2DL2
  • N2DL-2
  • NKG2D ligand 2
  • NKG2DL2
  • RAET1H
  • RAET1HNKG2DL2
  • retinoic acid early transcript 1 H
  • Retinoic acid early transcript 1H
  • UL16 binding protein 2
  • UL16-binding protein 2
  • ULBP2
  • ULBP-2

Background

Ligand for the NKG2D receptor, together with at least ULBP1 and ULBP3. ULBPs activate multiple signalingpathways in primary NK cells, resulting in the production of cytokines and chemokines. Binding of ULBPs ligands toNKG2D induces calcium mobilization and activation of the JAK2, STAT5, ERK and PI3K kinase/Akt signal transductionpathway. In CMV infected cells, interacts with soluble CMV glycoprotein UL16. The interaction with UL16 blocked theinteraction with the NKG2D receptor, providing a mechanism by which CMV infected cells might escape the immune system.UL16 also causes ULBP2 to be retained in the ER and cis-Golgi apparatus so that it does not reach the cell surface

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Secondary Antibodies

 

Isotype Controls

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Bioinformatics

Gene Symbol ULBP2