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UBE4B Antibody [Janelia Fluor® 585]

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Product Details

Summary
Reactivity Hu, MuSpecies Glossary
Applications IHC
Clonality
Polyclonal
Host
Rabbit
Conjugate
Janelia Fluor 585

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UBE4B Antibody [Janelia Fluor® 585] Summary

Immunogen
Produced in rabbits immunized with a synthetic peptide corresponding to the C-terminus of the Human UBE4B.
Predicted Species
Mouse (100%). Backed by our 100% Guarantee.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
UBE4B
Purity
Antigen and protein A Affinity-purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Immunohistochemistry-Paraffin
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Antigen and protein A Affinity-purified

Notes



Sold under license from the Howard Hughes Medical Institute, Janelia Research Campus.

Alternate Names for UBE4B Antibody [Janelia Fluor® 585]

  • E4
  • homologous to yeast UFD2
  • Homozygously deleted in neuroblastoma 1
  • homozygously deleted in neuroblastoma-1
  • KIAA0684HDNB1
  • UBE4B
  • ubiquitin conjugation factor E4 B
  • Ubiquitin fusion degradation protein 2
  • ubiquitination factor E4B (homologous to yeast UFD2)
  • ubiquitination factor E4B (UFD2 homolog, yeast)
  • ubiquitin-fusion degradation protein 2
  • UBOX3
  • UFD2
  • UFD2a
  • UFD2UFD2A

Background

The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes an additional conjugation factor, E4, which is involved in multiubiquitin chain assembly. This gene is also the strongest candidate in the neuroblastoma tumor suppressor genes.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Secondary Antibodies

 

Isotype Controls

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Bioinformatics

Gene Symbol UBE4B