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UBE4B Antibody (8F9)

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Western Blot: UBE4B Antibody (8F9) [H00010277-M01] - UBE4B monoclonal antibody (M01), clone 8F9 Analysis of UBE4B expression in Hela S3 NE.

Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, ELISA
Clone
8F9
Clonality
Monoclonal
Host
Mouse
Conjugate
Unconjugated

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UBE4B Antibody (8F9) Summary

Immunogen
UBE4B (NP_006039, 1075 a.a. ~ 1173 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. FKLLAEKVEEIVAKNARAEIDYSDAPDEFRDPLMDTLMTDPVRLPSGTIMDRSIILRHLLNSPTDPFNRQTLTESMLEPVPELKEQIQAWMREKQNSDH
Specificity
UBE4B - ubiquitination factor E4B (UFD2 homolog, yeast)
Isotype
IgG1 Kappa
Clonality
Monoclonal
Host
Mouse
Gene
UBE4B
Purity
IgG purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • ELISA
  • Western Blot 1:500
Application Notes
Antibody reactive against cell lysate and recombinant protein for western blot. It has also been used for ELISA.

Reactivity Notes

Human. Other species not tested.

Packaging, Storage & Formulations

Storage
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
Buffer
In 1x PBS, pH 7.4
Preservative
No Preservative
Purity
IgG purified

Notes

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for UBE4B Antibody (8F9)

  • E4
  • homologous to yeast UFD2
  • Homozygously deleted in neuroblastoma 1
  • homozygously deleted in neuroblastoma-1
  • KIAA0684HDNB1
  • UBE4B
  • ubiquitin conjugation factor E4 B
  • Ubiquitin fusion degradation protein 2
  • ubiquitination factor E4B (homologous to yeast UFD2)
  • ubiquitination factor E4B (UFD2 homolog, yeast)
  • ubiquitin-fusion degradation protein 2
  • UBOX3
  • UFD2
  • UFD2a
  • UFD2UFD2A

Background

The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes an additional conjugation factor, E4, which is involved in multiubiquitin chain assembly. This gene is also the strongest candidate in the neuroblastoma tumor suppressor genes. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Secondary Antibodies

 

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Bioinformatics

Gene Symbol UBE4B
Entrez
Uniprot