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TRAILR2/TNFRSF10B Antibody (HS201) [DyLight 650]

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications Flow, ICC/IF, IHC, IP, B/N
Clone
HS201
Clonality
Monoclonal
Host
Mouse
Conjugate
DyLight 650

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price
Alexa Fluor 350
NBP2-80066AF350
Alexa Fluor 350
NBP2-80067AF350
Alexa Fluor 405
NBP2-80067AF405
Alexa Fluor 405
NBP2-80066AF405
Alexa Fluor 488
NBP2-80067AF488
Alexa Fluor 488
NBP2-80066AF488
Alexa Fluor 532
NBP2-80066AF532
Alexa Fluor 532
NBP2-80067AF532
Alexa Fluor 594
NBP2-80066AF594
Alexa Fluor 594
NBP2-80067AF594
Alexa Fluor 647
NBP2-80066AF647
Alexa Fluor 647
NBP2-80067AF647
Alexa Fluor 700
NBP2-80066AF700
Alexa Fluor 700
NBP2-80067AF700
Alexa Fluor 750
NBP2-80066AF750
Alexa Fluor 750
NBP2-80067AF750
Allophycocyanin
NBP2-80066APC
Allophycocyanin
NBP2-80067APC
Biotin
NBP2-80067B
Biotin
NBP2-80066B
DyLight 350
NBP2-80067UV
DyLight 350
NBP2-80066UV
DyLight 405
NBP2-80067V
DyLight 405
NBP2-80066V
DyLight 488
NBP2-80066G
DyLight 488
NBP2-80067G
DyLight 550
NBP2-80066R
DyLight 550
NBP2-80067R
DyLight 594
NBP2-80066DL594
DyLight 594
NBP2-80067DL594
DyLight 650
NBP2-80066C
DyLight 680
NBP2-80066FR
DyLight 680
NBP2-80067FR
DyLight 755
NBP2-80066IR
DyLight 755
NBP2-80067IR
FITC
NBP2-80066F
FITC
NBP2-80067F
HRP
NBP2-80066H
HRP
NBP2-80067H
Janelia Fluor 549
NBP2-80067JF549
Janelia Fluor 549
NBP2-80066JF549
Janelia Fluor 646
NBP2-80066JF646
Janelia Fluor 646
NBP2-80067JF646
PE
NBP2-80067PE
PE
NBP2-80066PE
PerCP
NBP2-80067PCP
PerCP
NBP2-80066PCP
Unconjugated
NBP2-80066
View Available Formulations
Catalog# & Formulation Size Price
Standard Formulation
NBP2-80066
BSA Free
NBP2-80066
Azide and BSA Free
NBP2-80067
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TRAILR2/TNFRSF10B Antibody (HS201) [DyLight 650] Summary

Immunogen
Recombinant human TRAILR2/TNFRSF10B (DR5).
Specificity
Recognizes human TRAILR2/TNFRSF10B. Does not cross-react with human TRAIL-R1, -R3 or -R4.
Isotype
IgG1
Clonality
Monoclonal
Host
Mouse
Gene
TNFRSF10B
Purity
Protein G purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.
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Applications/Dilutions

Dilutions
  • Block/Neutralize
  • Flow Cytometry
  • Immunocytochemistry/ Immunofluorescence
  • Immunohistochemistry
  • Immunoprecipitation
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Protein G purified

Notes



DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

Alternate Names for TRAILR2/TNFRSF10B Antibody (HS201) [DyLight 650]

  • CD262 antigen
  • CD262
  • death domain containing receptor for TRAIL/Apo-2L
  • Death receptor 5
  • DR5
  • DR5TRICK2B
  • Fas-like protein
  • KILLER/DR5
  • KILLERapoptosis inducing protein TRICK2A/2B
  • TNF-related apoptosis-inducing ligand receptor 2
  • TNFRSF10B
  • TRAIL R2
  • TRAIL receptor 2
  • TRAILR2
  • TRAIL-R2apoptosis inducing receptor TRAIL-R2
  • TRAILR2cytotoxic TRAIL receptor-2
  • TRICK2
  • TRICK2A
  • TRICKB
  • tumor necrosis factor receptor superfamily member 10B
  • tumor necrosis factor receptor superfamily, member 10b
  • tumor necrosis factor receptor-like protein ZTNFR9
  • ZTNFR9

Background

Apoptosis is induced by certain cytokines including TNF and Fas ligand in the TNF family through their death domain containing receptors. TRAIL/Apo2L is a new member of the TNF family. DR4 was recently identified as the receptor for TRAIL. A novel death domain containing receptor for TRAIL was more recently identified and designated DR5, Apo2, TRAIL-R2, TRICK2, or KILLER by several groups independently (1-2). Like DR4, DR5 transcript is widely expressed in normal tissues and in many types of tumor cells. DR5 binds to TRAIL and mediates TRAIL induced cell death. Overexpression of DR5 induces apoptosis and activates NF-kB.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol TNFRSF10B