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TRAILR2/TNFRSF10B Antibody (71908) [PE/Cy7]

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications Flow
Clone
71908
Clonality
Monoclonal
Host
Mouse
Conjugate
PE/Cy7

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price
Alexa Fluor 350
FAB6311U-100UG
Alexa Fluor 405
FAB6311V-100UG
Alexa Fluor 488
FAB6311G-025
Alexa Fluor 488
FAB6311G-100
Alexa Fluor 532
FAB6311X
Alexa Fluor 594
FAB6311T-100UG
Alexa Fluor 700
FAB6311N-025
Alexa Fluor 700
FAB6311N-100
Alexa Fluor 750
FAB6311S-100UG
Allophycocyanin
FAB6311A-100
Allophycocyanin
FAB6311A-025
Allophycocyanin/Cy7
FAB6311APCCY7
Biotin
FAB6311B
DyLight 350
FAB6311D
DyLight 405
FAB6311E
DyLight 488
FAB6311K
DyLight 550
FAB6311L
DyLight 594
FAB6311M
DyLight 650
FAB6311W
DyLight 680
FAB6311Y
DyLight 755
FAB6311Z
FITC
FAB6311F
HRP
FAB6311H
Janelia Fluor 525
FAB6311JF525
Janelia Fluor 549
FAB6311I
Janelia Fluor 646
FAB6311J
Janelia Fluor 669
FAB6311JF669
PE/Atto594
FAB6311PEATT594
PE/Cy5.5
FAB6311PECY55
Phycoerythrin
FAB6311P-025
Phycoerythrin
FAB6311P-100
Unconjugated
MAB6311
View Available Formulations
Catalog# & Formulation Size Price
Standard Formulation
MAB6311
Carrier Free
MAB6311
Carrier Free
MAB6311-SP
Carrier Free
FAB6311N-100
Carrier Free
FAB6311N-025
Carrier Free
FAB6311A-100
Carrier Free
FAB6311A-025
Carrier Free
FAB6311G-100
Carrier Free
FAB6311G-025
Carrier Free
FAB6311P-100
Carrier Free
FAB6311P-025
Carrier Free
FAB6311V-100UG
Carrier Free
FAB6311U-100UG
Carrier Free
FAB6311T-100UG
Carrier Free
FAB6311S-100UG
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TRAILR2/TNFRSF10B Antibody (71908) [PE/Cy7] Summary

Immunogen
Mouse myeloma cell line NS0-derived recombinant human TRAIL R2/TNFRSF10B
Ile56-Glu182
Accession # O14763
Specificity
Detects human TRAIL R2 in direct ELISAs and Western blots. In direct ELISAs, does not cross-react with recombinant human (rh) TRAIL R1, rhTRAIL R3, rhTRAIL R4, or recombinant mouse TRAIL R2.
Isotype
IgG2b
Clonality
Monoclonal
Host
Mouse
Gene
TNFRSF10B
Purity
Protein A or G purified from hybridoma culture supernatant
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.
Learn about the Innovator's Reward

Applications/Dilutions

Dilutions
  • Flow Cytometry
Application Notes
Optimal dilution of this antibody should be experimentally determined. For optimal results using our Tandem dyes, please avoid prolonged exposure to light or extreme temperature fluctuations. These can lead to irreversible degradation or decoupling. When staining intracellular targets, specific attention to the fixation and permeabilization steps in your flow protocol may be required. Please contact our technical support team at technical@novusbio.com if you have any questions.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark. Do not freeze.
Buffer
PBS
Preservative
0.05% Sodium Azide
Purity
Protein A or G purified from hybridoma culture supernatant

Alternate Names for TRAILR2/TNFRSF10B Antibody (71908) [PE/Cy7]

  • CD262 antigen
  • CD262
  • death domain containing receptor for TRAIL/Apo-2L
  • Death receptor 5
  • DR5
  • DR5TRICK2B
  • Fas-like protein
  • KILLER/DR5
  • KILLERapoptosis inducing protein TRICK2A/2B
  • TNF-related apoptosis-inducing ligand receptor 2
  • TNFRSF10B
  • TRAIL R2
  • TRAIL receptor 2
  • TRAILR2
  • TRAIL-R2apoptosis inducing receptor TRAIL-R2
  • TRAILR2cytotoxic TRAIL receptor-2
  • TRICK2
  • TRICK2A
  • TRICKB
  • tumor necrosis factor receptor superfamily member 10B
  • tumor necrosis factor receptor superfamily, member 10b
  • tumor necrosis factor receptor-like protein ZTNFR9
  • ZTNFR9

Background

Apoptosis is induced by certain cytokines including TNF and Fas ligand in the TNF family through their death domain containing receptors. TRAIL/Apo2L is a new member of the TNF family. DR4 was recently identified as the receptor for TRAIL. A novel death domain containing receptor for TRAIL was more recently identified and designated DR5, Apo2, TRAIL-R2, TRICK2, or KILLER by several groups independently (1-2). Like DR4, DR5 transcript is widely expressed in normal tissues and in many types of tumor cells. DR5 binds to TRAIL and mediates TRAIL induced cell death. Overexpression of DR5 induces apoptosis and activates NF-kB.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol TNFRSF10B