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TMEM97 Recombinant Protein Antigen

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Summary
Reactivity HuSpecies Glossary
Applications AC

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TMEM97 Recombinant Protein Antigen Summary

Description
A recombinant protein antigen with a N-terminal His6-ABP tag corresponding to human TMEM97.

Source: E. coli

Amino Acid Sequence: FEDFSKASGFKGQRPETLHERLT

Fusion Tag: N-terminal His6ABP (ABP = Albumin Binding Protein derived from Streptococcal Protein G)

This product is intended to be used as a blocking antigen for antibody competition assays. Any other use of this antigen is done at the risk of the user. The use of this product for commercial production is strictly prohibited. Please contact technical support if you have any questions.
Source
E. coli
Protein/Peptide Type
Recombinant Protein Antigen
Gene
TMEM97
Purity
>80% by SDS-PAGE and Coomassie blue staining

Applications/Dilutions

Dilutions
  • Antibody Competition 10 - 100 molar excess
Application Notes
This recombinant antigen is only intended to be used as a blocking agent to confirm antibody specificity with the corresponding antibody, catalog number NBP1-92522.

It is purified by IMAC chromatography, and the expected concentration is greater than 0.5 mg/ml.

For current lot information, including availability, please contact our technical support team click nb-technical@bio-techne.com

Theoretical MW
20 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

Storage
Store at -20C. Avoid freeze-thaw cycles.
Buffer
PBS and 1M Urea, pH 7.4.
Preservative
No Preservative
Purity
>80% by SDS-PAGE and Coomassie blue staining

Alternate Names for TMEM97 Recombinant Protein Antigen

  • MAC30
  • MAC30Protein MAC30
  • S2R
  • Sigma2 receptor
  • Sigma-2 receptor
  • TMEM97
  • transmembrane protein 97

Background

TMEM97, or MAC30, is a conserved transmembrane protein that helps regulate cellular cholesterol levels through colocalization with NPC1. TMEM97 has also been linked to several cancers including breast, pancreatic, colorectal and ovarian cancers.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Peptides and proteins are guaranteed for 3 months from date of receipt.

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TMEM97 Recombinant Protein Antigen
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Check out the latest blog posts on TMEM97.
First Commercial TMEM97 Antibody Launched
We at Novus Biologicals recently created excitement when we added TMEM97 antibody to our database. We are the first antibody suppliers to offer a product targeted to TMEM97.TMEM97 (transmembrane protein 97, also known as MAC30) is a multi-cross tran...  Read full blog post.
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Bioinformatics

Gene Symbol TMEM97