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Thyroglobulin Antibody (CL0164)

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Western Blot: Thyroglobulin Antibody (CL0164) [NBP2-14784] - Lane 1: Marker [kDa], Lane 2: Human normal thyroid

Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, IHC
Clone
CL0164
Clonality
Monoclonal
Host
Mouse
Conjugate
Unconjugated

Order Details

  • Size / Catalog#QtyPrice
    NBP2-14784-25ul
    25ul
    $329.00
    4-6 Business Days
    NBP2-14784
    0.1 ml
    $519.00
    4-6 Business Days
Shipping $45.00 per order
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Support & Research

Thyroglobulin Antibody (CL0164) Summary

Immunogen
This antibody was developed against Recombinant Protein corresponding to amino acids:KMCSADYADLLQTFQVFILDELTARGFCQIQVKTFGTLVSIPVCNNSSVQVGCLTRERLGVNVTWKSRLEDIPVASLPDLHDIERALVGKDLLGRFTDLIQSGSFQLHLDSKTFPAETIRFLQGDHFGTSPRTWFGCSEGFYQVLTSEASQDGLGCVKCPEGS
Epitope
HDIERALVGKDLLGR
Isotype
IgG2b
Clonality
Monoclonal
Host
Mouse
Gene
TG
Purity
Protein A purified
Innovator's Reward
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Applications/Dilutions

Dilutions
  • Immunohistochemistry 1:500 - 1:1000
  • Immunohistochemistry-Paraffin 1:500-1:1000
  • Western Blot 1 ug/ml
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.
Control Peptide
Thyroglobulin Recombinant Protein Antigen (NBP2-14784PEP)

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.2) and 40% Glycerol
Preservative
0.02% Sodium Azide
Purity
Protein A purified

Alternate Names for Thyroglobulin Antibody (CL0164)

  • AITD3
  • AITD3TGN
  • cog
  • TDH3
  • Tg
  • TGN
  • Thyroglobulin

Background

Thyroglobulin is synthesized by the follicular epithelial cells of the thyroid. Thyroglobulin is the glycoprotein precursor to the thyroid hormones. Its synthesis and metabolism have seemingly wasteful features. It has a molecular weight of 660,000, with 2 identical subunits of MW 300,000 and 10% sugars; yet its complete hydrolysis yields only 2 to 4 molecules of the iodothyroxines T4 and T3. Baas et al. (1986) showed that the TG gene encodes an 8.7-kb mRNA, covers at least 300 kb of genomic DNA and contains at least 37 exons separated by introns as large as 64 kb. A striking structural difference between the 5-prime and 3-prime parts of the gene suggested that it is composed of 2 evolutionarily different regions. The first 30 kb of DNA encodes 3 kb of the mRNA yielding an exon:intron ratio of 1:10, whereas the remaining 270 kb encodes 5.7 kb of the mRNA with a ratio of 1.47.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol TG