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TDG Antibody [Biotin]

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, IHC
Clonality
Polyclonal
Host
Rabbit
Conjugate
Biotin

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price
Alexa Fluor 350
NBP2-32248AF350
Alexa Fluor 405
NBP2-32248AF405
Alexa Fluor 488
NBP2-32248AF488
Alexa Fluor 532
NBP2-32248AF532
Alexa Fluor 594
NBP2-32248AF594
Alexa Fluor 647
NBP2-32248AF647
Alexa Fluor 700
NBP2-32248AF700
Alexa Fluor 750
NBP2-32248AF750
CoraFluor 1
NBP2-32248CL1
DyLight 350
NBP2-32248UV
DyLight 405
NBP2-32248V
DyLight 488
NBP2-32248G
DyLight 550
NBP2-32248R
DyLight 594
NBP2-32248DL594
DyLight 650
NBP2-32248C
DyLight 680
NBP2-32248FR
DyLight 755
NBP2-32248IR
FITC
NBP2-32248F
HRP
NBP2-32248H
Janelia Fluor 525
NBP2-32248JF525
Janelia Fluor 549
NBP2-32248JF549
Janelia Fluor 585
NBP2-32248JF585
Janelia Fluor 635
NBP2-32248JF635
Janelia Fluor 646
NBP2-32248JF646
Janelia Fluor 669
NBP2-32248JF669
Unconjugated
NBP2-32248
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TDG Antibody [Biotin] Summary

Immunogen
The immunogen this antibody was made to, maps to a region between residue 360 to 410 of human Thymine-DNA Glycosylase using the numbering given in entry NP_003202.3 (GeneID 6996).
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
TDG
Purity
Immunogen affinity purified
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Applications/Dilutions

Dilutions
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin
  • Western Blot
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
PBS
Preservative
0.05% Sodium Azide
Purity
Immunogen affinity purified

Alternate Names for TDG Antibody [Biotin]

  • EC 3.2.2.29
  • TDG
  • thymine-DNA glycosylaseG/T mismatch-specific thymine DNA glycosylase

Background

Thymine DNA glycosylase is encoded by this gene belongs to the TDG/mug DNA glycosylase family. Thymine-DNA glycosylase (TDG) removes thymine moieties from G/T mismatches by hydrolyzing the carbon-nitrogen bond between the sugar-phosphate backbone of DNA and the mispaired thymine. With lower activity, this enzyme also removes thymine from C/T and T/T mispairings. TDG can also remove uracil and 5-bromouracil from mispairings with guanine. This enzyme plays a central role in cellular defense against genetic mutation caused by the spontaneous deamination of 5-methylcytosine and cytosine. This gene may have a pseudogene in the p arm of chromosome 12. [provided by RefSeq]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Secondary Antibodies

 

Isotype Controls

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Bioinformatics

Gene Symbol TDG