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TACI/TNFRSF13B/CVID Antibody (166010) [Phycoerythrin]

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Mouse splenocytes were stained with Rat Anti-Mouse B220/CD45R Fluorescein-conjugated Monoclonal Antibody (Catalog # FAB1217F) and either (A) Rat Anti-Mouse TACI/TNFRSF13B PE-conjugated Monoclonal Antibody (Catalog # FAB1041P) or (B) Rat IgG2APhycoerythrin Isotype Control (Catalog # IC006P). View our protocol for Staining Membrane-associated Proteins.
Mouse splenocytes were stained with Rat Anti-Mouse B220/CD45R Fluorescein-conjugated Monoclonal Antibody (Catalog # FAB1217F) and either (A) Rat Anti-Mouse TACI/TNFRSF13B PE-conjugated Monoclonal Antibody (Catalog # ...read more

Product Details

Summary
Reactivity MuSpecies Glossary
Applications Flow
Clone
166010
Clonality
Monoclonal
Host
Rat
Conjugate
Phycoerythrin

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price
Alexa Fluor 350
FAB1041U-100UG
Alexa Fluor 405
FAB1041V-100UG
Alexa Fluor 488
FAB1041G-100UG
Alexa Fluor 532
FAB1041X
Alexa Fluor 594
FAB1041T-100UG
Alexa Fluor 647
FAB1041R-100UG
Alexa Fluor 700
FAB1041N-100UG
Alexa Fluor 750
FAB1041S-100UG
Allophycocyanin
FAB1041A
Allophycocyanin/Cy7
FAB1041APCCY7
Biotin
FAB1041B
DyLight 350
FAB1041D
DyLight 405
FAB1041E
DyLight 488
FAB1041K
DyLight 550
FAB1041L
DyLight 594
FAB1041M
DyLight 650
FAB1041W
DyLight 680
FAB1041Y
DyLight 755
FAB1041Z
FITC
FAB1041F
HRP
FAB1041H
Janelia Fluor 525
FAB1041JF525
Janelia Fluor 549
FAB1041I
Janelia Fluor 585
FAB1041JF585
Janelia Fluor 635
FAB1041JF635
Janelia Fluor 646
FAB1041J
Janelia Fluor 669
FAB1041JF669
PE/Atto594
FAB1041PEATT594
PE/Cy5.5
FAB1041PECY55
PE/Cy7
FAB1041PECY7
PerCP
FAB1041C
Unconjugated
MAB1041
View Available Formulations
Catalog# & Formulation Size Price
Standard Formulation
MAB1041
Carrier Free
FAB1041A
Carrier Free
MAB1041
Carrier Free
MAB1041-SP
Carrier Free
FAB1041V-100UG
Carrier Free
FAB1041U-100UG
Carrier Free
FAB1041T-100UG
Carrier Free
FAB1041S-100UG
Carrier Free
FAB1041R-100UG
Carrier Free
FAB1041N-100UG
Carrier Free
FAB1041G-100UG
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TACI/TNFRSF13B/CVID Antibody (166010) [Phycoerythrin] Summary

Immunogen
Mouse myeloma cell line NS0-derived recombinant mouse TACI/TNFRSF13B
Phe5-Thr129
Accession # Q9ET35
Specificity
Detects mouse TACI/TNFRSF13B in direct ELISAs and Western blots. In direct ELISAs and Western blots, no cross‑reactivity with recombinant human (rh) TACI or rhBCMA is observed.
Source
N/A
Isotype
IgG2a
Clonality
Monoclonal
Host
Rat
Gene
TNFRSF13B
Purity Statement
Protein A or G purified from hybridoma culture supernatant
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.
Learn about the Innovator's Reward

Applications/Dilutions

Dilutions
  • Flow Cytometry 10 uL/10^6 cells
Publications
Read Publications using
FAB1041P in the following applications:

Packaging, Storage & Formulations

Storage
Protect from light. Do not freeze.
  • 12 months from date of receipt, 2 to 8 °C as supplied.
Buffer
Supplied in a saline solution containing BSA and Sodium Azide.
Preservative
Sodium Azide

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for TACI/TNFRSF13B/CVID Antibody (166010) [Phycoerythrin]

  • CD267 antigen
  • CD267
  • CVID
  • CVID2
  • FLJ39942
  • MGC133214
  • TACI
  • TACIMGC39952
  • TNFRSF13B
  • TNFRSF14B
  • Transmembrane activator and CAML interactor
  • tumor necrosis factor receptor 13B
  • tumor necrosis factor receptor superfamily member 13B
  • tumor necrosis factor receptor superfamily, member 13B

Background

TACI, Transmembrane Activator and CAML-Interactor, is a member of the TNF receptor superfamily and has been designated TNFRSF13B. TACI is a type III membrane protein with an extracellular N-terminus in the absence of a cleaved signal sequence. The extracellular region of TACI contains two cysteine-rich domains. Within the TNFRSF, it shares the highest homology with B cell Maturation Factor (BCMA). TACI and BCMA have both been shown to bind APRIL and BAFF, members of the TNF ligand superfamily. TACI is expressed on the cell surface of B cells and activated, but not resting, T cells. Analogous to BCMA, data suggests that TACI may play an important role in B cell development, function and regulation. Mature mouse TACI is a 249 amino acid (aa) protein consisting of a 129 aa extracellular domain, a 20 aa transmembrane domain, and a 100 aa intracellular domain. Mouse and human TACI share 54% aa identity.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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N/A IL-6 [HRP]
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TACI/TNFRSF13B/CVID An ...
FAB1041P
TACI/TNFRSF13B/CVID Antibody (166010) [Phycoerythrin]
Species: Mu
Applications: Flow

Publications for TACI/TNFRSF13B/CVID Antibody (FAB1041P)(5)

We have publications tested in 1 confirmed species: Mouse.

We have publications tested in 1 application: Flow Cytometry.


Filter By Application
Flow Cytometry
(5)
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Mouse
(5)
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Showing Publications 1 - 5 of 5.
Publications using FAB1041P Applications Species
Uslu K, Coleman A, Allman W, Katsenelson N, Bram R, Alugupalli K, Akkoyunlu M Impaired B cell receptor signaling is responsible for reduced TACI expression and function in X-linked immunodeficient mice. J Immunol, 2014-03-19;192(8):3582-95. 2014-03-19 [PMID: 24646744] (Flow Cytometry, Mouse) Flow Cytometry Mouse
Figgett W, Fairfax K, Vincent F, Le Page M, Katik I, Deliyanti D, Quah P, Verma P, Grumont R, Gerondakis S, Hertzog P, O'Reilly L, Strasser A, Mackay F The TACI receptor regulates T-cell-independent marginal zone B cell responses through innate activation-induced cell death. Immunity, 2013-09-05;39(3):573-83. 2013-09-05 [PMID: 24012421] (Flow Cytometry, Mouse) Flow Cytometry Mouse
Crowley JE, Stadanlick JE, Cambier JC, Cancro MP FcgammaRIIB signals inhibit BLyS signaling and BCR-mediated BLyS receptor up-regulation. Blood, 2008-09-12;113(7):1464-73. 2008-09-12 [PMID: 18791164] (Flow Cytometry, Mouse) Flow Cytometry Mouse
Kanswal S, Katsenelson N, Selvapandiyan A, Bram RJ, Akkoyunlu M Deficient TACI expression on B lymphocytes of newborn mice leads to defective Ig secretion in response to BAFF or APRIL. J. Immunol., 2008-07-15;181(2):976-90. 2008-07-15 [PMID: 18606649] (Flow Cytometry, Mouse) Flow Cytometry Mouse
Hardenberg G, Fernandez L, Hendriks J, Chebli K, Jacquet C, Sitbon M, Hahne M, Medema JP APRIL facilitates viral-induced erythroleukemia but is dispensable for T cell immunity and lymphomagenesis. J. Leukoc. Biol., 2008-05-15;84(2):380-8. 2008-05-15 [PMID: 18483203] (Flow Cytometry, Mouse) Flow Cytometry Mouse

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Bioinformatics

Gene Symbol TNFRSF13B
Uniprot