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SPG3A Antibody (1F6B12) - BSA Free

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Western Blot: SPG3A Antibody (1F6B12) [NBP2-61886] - Analysis using ATL1 mAb against human ATL1 (AA: 1-100) recombinant protein. (Expected MW is 41.3 kDa)
Western Blot: SPG3A Antibody (1F6B12) [NBP2-61886] - Analysis using ATL1 mAb against HEK293 (1) and ATL1 (AA: 1-100)-hIgGFc transfected HEK293 (2) cell lysate.
ELISA: SPG3A Antibody (1F6B12) [NBP2-61886] - Black line: Control Antigen (100 ng);Purple line: Antigen (10ng); Blue line: Antigen (50 ng); Red line:Antigen (100 ng)

Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, ELISA
Clone
1F6B12
Clonality
Monoclonal
Host
Mouse
Conjugate
Unconjugated
Format
BSA Free
Concentration
1 mg/ml

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SPG3A Antibody (1F6B12) - BSA Free Summary

Immunogen
Purified recombinant fragment of human SPG3A (AA: 1-100) expressed in E. Coli.
Isotype
IgG1
Clonality
Monoclonal
Host
Mouse
Gene
ATL1
Purity
Protein G purified
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Applications/Dilutions

Dilutions
  • ELISA 1:100-1:2000
  • Western Blot 1:100-1:2000
Theoretical MW
63.5 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS
Preservative
0.05% Sodium Azide
Concentration
1 mg/ml
Purity
Protein G purified

Alternate Names for SPG3A Antibody (1F6B12) - BSA Free

  • AD-FSP
  • ATL1
  • atlastin GTPase 1
  • atlastin1
  • atlastin-1
  • Brain-specific GTP-binding protein
  • EC 3.6.5.-
  • FSP1
  • GBP3
  • GBP-3
  • GTP-binding protein 3
  • Guanine nucleotide-binding protein 3
  • guanylate-binding protein 3
  • hGBP3
  • Spastic paraplegia 3 protein A
  • spastic paraplegia 3A (autosomal dominant)
  • SPG3
  • SPG3A
  • SPG3AhGBP3

Background

The protein encoded by this gene is a GTPase and a Golgi body transmembrane protein. The encoded protein can form a homotetramer and has been shown to interact with spastin and with mitogen-activated protein kinase kinase kinase kinase 4. This protein may be involved in axonal maintenance as evidenced by the fact that defects in this gene are a cause of spastic paraplegia type 3. Three transcript variants encoding two different isoforms have been found for this gene.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol ATL1