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SORBS1 Antibody

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Immunohistochemistry-Paraffin: SORBS1 Antibody [NB100-1046] - (2.5ug/ml) staining of paraffin embedded Human Skeletal Muscle. Steamed antigen retrieval with citrate buffer pH 6, AP-staining.
Immunohistochemistry-Paraffin: SORBS1 Antibody [NB100-1046] - (2.5ug/ml) staining of paraffin embedded Human Skeletal Muscle. Steamed antigen retrieval with citrate buffer pH 6, AP-staining.

Product Details

Summary
Reactivity Hu, Mu, Rt, PoSpecies Glossary
Applications ELISA, IHC
Clonality
Polyclonal
Host
Goat
Conjugate
Unconjugated
Concentration
0.5 mg/ml

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SORBS1 Antibody Summary

Immunogen
Peptide with sequence C-GTFPGNYVKPLYL corresponding to C-Terminus according to NP_006425.2, NP_056200.1, NP_001030126.1, NP_001030127.1, NP_001030128.1, NP_079267.1, NP_001030129.1.
Specificity
This antibody is expected to recognize all seven reported isoforms (NP_006425.2, NP_056200.1, NP_001030126.1, NP_001030127.1, NP_001030128.1, NP_079267.1 and NP_001030129.1).
Predicted Species
Mouse (100%), Rat (100%), Porcine (100%). Backed by our 100% Guarantee.
Isotype
IgG
Clonality
Polyclonal
Host
Goat
Gene
SORBS1
Purity
Immunogen affinity purified
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Applications/Dilutions

Dilutions
  • Immunohistochemistry 2.5 ug/ml
  • Immunohistochemistry-Paraffin 2.5 ug/ml
  • Peptide ELISA Detection limit 1:16000
Application Notes
WB: No signal obtained yet but low background observed in human heart and 293 lysates at up to 2ug/ml. IHC-P: Human skeletal muscle shows spotty staining on muscle fibres in longitudinal section. Data obtained from a previous batch (different goat).
Publications
Read Publication using NB100-1046.

Reactivity Notes

Predicted cross-reactivity based on sequence identity: Mouse, Rat, Porcine.

Packaging, Storage & Formulations

Storage
Store at -20C. Avoid freeze-thaw cycles.
Buffer
Tris saline (20 mM Tris pH 7.3, 150 mM NaCl), 0.5% BSA
Preservative
0.02% Sodium Azide
Concentration
0.5 mg/ml
Purity
Immunogen affinity purified

Alternate Names for SORBS1 Antibody

  • c-Cbl associated protein
  • c-Cbl-associated protein
  • DKFZp451C066
  • DKFZp586P1422
  • Fas-ligand associated factor 2
  • FLAF2
  • KIAA0894
  • KIAA1296CAPSH3D5SH3P12FLJ12406
  • ponsin
  • R85FL
  • SH3 domain protein 5
  • SH3-domain protein 5 (ponsin)
  • sh3p12
  • SORB1
  • sorbin and SH3 domain containing 1
  • sorbin and SH3 domain-containing protein 1

Background

SORBS1 plays a role in tyrosine phosphorylation of CBL by linking CBL to the insulin receptor. Required for insulin-stimulated glucose transport. Involved in formation of actin stress fibers and focal adhesions

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for SORBS1 Antibody (NB100-1046)(1)


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Bioinformatics

Gene Symbol SORBS1
Entrez
Uniprot