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SMG1 Antibody

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Immunohistochemistry-Paraffin: SMG1 Antibody [NBP2-37870] - Staining of human small intestine shows strong cytoplasmic positivity in glandular cells.

Product Details

Summary
Reactivity Hu, MuSpecies Glossary
Applications IHC
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated

Order Details

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SMG1 Antibody Summary

Immunogen
This antibody was developed against a recombinant protein corresponding to amino acids: AFDGMFAQVETAFSLLVEKLNKMEIPIAWRKIDIIREARSTQVNFFDDDNHRQVLEEIFFLKRLQTIKEFFRLCGTFSKTLSGSSSLEDQNTVNGPVQIVNVKTL
Predicted Species
Mouse (98%). Backed by our 100% Guarantee.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
SMG1
Purity
Immunogen affinity purified
Innovator's Reward
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Applications/Dilutions

Dilutions
  • Immunohistochemistry 1:200 - 1:500
  • Immunohistochemistry-Paraffin 1:200 - 1:500
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.
Control Peptide
SMG1 Protein (NBP2-37870PEP)

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.2) and 40% Glycerol
Preservative
0.02% Sodium Azide
Purity
Immunogen affinity purified

Alternate Names for SMG1 Antibody

  • ATXserine/threonine-protein kinase SMG1
  • EC 2.7.11
  • EC 2.7.11.1
  • hSMG-1,61E3.4
  • KIAA0421phosphatidylinositol 3-kinase-related protein kinase
  • Lambda/iota protein kinase C-interacting protein
  • Lambda-interacting protein
  • LIPPI-3-kinase-related kinase SMG-1
  • phosphatidylinositol 3-kinase-related kinase
  • SMG1 homolog, phosphatidylinositol 3-kinase-related kinase (C. elegans)
  • SMG-1

Background

SMG1 encodes a protein involved in nonsense-mediated mRNA decay (NMD) as part of the mRNA surveillance complex. The protein has kinase activity and is thought to function in NMD by phosphorylating the regulator of nonsense transcripts 1 protein. Alternative spliced transcript variants have been described, but their full-length natures have not been determined.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Secondary Antibodies

 

Isotype Controls

Additional SMG1 Products

Array NBP2-37870

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Bioinformatics

Gene Symbol SMG1
Uniprot