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SLC6A4/5-HTTLPR/Serotonin transporter Antibody (632705) [Unconjugated]

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HEK293 human embryonic kidney cell line transfected with (A) human SLC6A4/5-HTTLPR or (B) irrelevant protein, and eGFP was stained with Mouse Anti-Human SLC6A4/5-HTTLPR Monoclonal Antibody (Catalog # MAB17292) followed ...read more

Product Details

Summary
Reactivity HuSpecies Glossary
Applications Flow
Clone
632705
Clonality
Monoclonal
Host
Mouse
Conjugate
Unconjugated

Order Details

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SLC6A4/5-HTTLPR/Serotonin transporter Antibody (632705) [Unconjugated] Summary

Immunogen
Human SLC6A4/5-HTTLPR synthetic peptide
Accession # P31645
Specificity
Detects human SLC6A4/5-HTTLPR in direct ELISAs.
Source
N/A
Isotype
IgG2a
Clonality
Monoclonal
Host
Mouse
Purity Statement
Protein A or G purified from hybridoma culture supernatant
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Flow Cytometry 0.25 ug/10^6 cells

Packaging, Storage & Formulations

Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.
Buffer
Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.
Reconstitution Instructions
Reconstitute at 0.5 mg/mL in sterile PBS.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for SLC6A4/5-HTTLPR/Serotonin transporter Antibody (632705) [Unconjugated]

  • 5HT transporter
  • 5-HT Transporter
  • 5-HTT
  • 5HTTLPR
  • 5-HTTLPR
  • hSERT
  • HTT5-hydroxytryptamine transporter
  • Na+/Cl- dependent serotonin transporter
  • OCD1
  • Serotonin Transporter 1
  • SERT
  • SLC6A4
  • sodium-dependent serotonin transporter
  • solute carrier family 6 (neurotransmitter transporter, serotonin), member 4,5-HTTLPR
  • Solute carrier family 6 member 4,5HTT

Background

SLC6A4 is an integral membrane protein that transports the neurotransmitter serotonin from synaptic spaces into pre-synaptic neurons. It terminates the action of serotonin and recycles it in a sodium-dependent manner. A repeat length polymorphism in the promoter of SLC6A4 has been shown to affect the rate of serotonin uptake and may play a role in sudden infant death syndrome, aggressive behavior in Alzheimer disease patients,and depression-susceptibility in people experiencing emotional trauma.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Secondary Antibodies

 

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