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Siglec-7/CD328 Antibody (194211) [DyLight 405]

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications Flow, CyTOF-ready
Clone
194211
Clonality
Monoclonal
Host
Mouse
Conjugate
DyLight 405

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price
Alexa Fluor 350
FAB11381U-100UG
Alexa Fluor 405
FAB11381V-100UG
Alexa Fluor 488
FAB11381G-025
Alexa Fluor 488
FAB11381G-100
Alexa Fluor 532
FAB11381X
Alexa Fluor 594
FAB11381T-100UG
Alexa Fluor 647
FAB11381R-100UG
Alexa Fluor 700
FAB11381N-100UG
Alexa Fluor 750
FAB11381S-100UG
Allophycocyanin
FAB11381A-025
Allophycocyanin
FAB11381A-100
Allophycocyanin/Cy7
FAB11381APCCY7
Biotin
FAB11381B
CoraFluor 1
FAB11381CL1
DyLight 350
FAB11381D
DyLight 488
FAB11381K
DyLight 550
FAB11381L
DyLight 594
FAB11381M
DyLight 650
FAB11381W
DyLight 680
FAB11381Y
DyLight 755
FAB11381Z
FITC
FAB11381F
HRP
FAB11381H
Janelia Fluor 525
FAB11381JF525
Janelia Fluor 549
FAB11381I
Janelia Fluor 585
FAB11381JF585
Janelia Fluor 635
FAB11381JF635
Janelia Fluor 646
FAB11381J
Janelia Fluor 669
FAB11381JF669
PE/Atto594
FAB11381PEATT594
PE/Cy5.5
FAB11381PECY55
PE/Cy7
FAB11381PECY7
PerCP
FAB11381C
Phycoerythrin
FAB11381P-100
Phycoerythrin
FAB11381P-025
Unconjugated
MAB11381
mFluor Violet 450 SE
FAB11381MFV450
mFluor Violet 500 SE
FAB11381MFV500
mFluor Violet 610 SE
FAB11381MFV610
View Available Formulations
Catalog# & Formulation Size Price
Standard Formulation
MAB11381
Carrier Free
FAB11381P-025
Carrier Free
FAB11381P-100
Carrier Free
MAB11381
Carrier Free
FAB11381A-025
Carrier Free
FAB11381A-100
Carrier Free
FAB11381G-025
Carrier Free
FAB11381G-100
Carrier Free
MAB11381-SP
Carrier Free
FAB11381V-100UG
Carrier Free
FAB11381U-100UG
Carrier Free
FAB11381T-100UG
Carrier Free
FAB11381S-100UG
Carrier Free
FAB11381R-100UG
Carrier Free
FAB11381N-100UG
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Siglec-7/CD328 Antibody (194211) [DyLight 405] Summary

Immunogen
Mouse myeloma cell line NS0-derived recombinant human Siglec-7
Gln19-Gly357 (predicted)
Accession # Q9Y286
Specificity
Detects human Siglec-7 in direct ELISAs. In direct ELISAs, no cross-reactivity with recombinant human Siglec-6, -8, -9 or recombinant Siglec-E is observed.
Isotype
IgG1
Clonality
Monoclonal
Host
Mouse
Gene
SIGLEC7
Purity
Protein A or G purified from hybridoma culture supernatant
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.
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Applications/Dilutions

Dilutions
  • CyTOF-reported
  • Flow Cytometry
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Protein A or G purified from hybridoma culture supernatant

Notes

DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

Alternate Names for Siglec-7/CD328 Antibody (194211) [DyLight 405]

  • Adhesion inhibitory receptor molecule 1
  • adhesion inhibitory receptor molecule 1, siglec-7
  • AIRM1
  • AIRM-1
  • AIRM1QA79 membrane protein
  • CD328 antigen
  • CD328
  • CDw328
  • D-siglec
  • p75
  • p75/AIRM1
  • QA79
  • sialic acid binding Ig-like lectin 7
  • sialic acid binding immunoglobulin-like lectin 7
  • sialic acid-binding Ig-like lectin 7
  • Siglec7
  • Siglec-7

Background

Putative adhesion molecule that mediates sialic-acid dependent binding to cells. Preferentially binds toalpha-2,3- and alpha-2,6-linked sialic acid. Also binds disialogangliosides (disialogalactosyl globoside, disialyllactotetraosylceramide and disialyl GalNAc lactotetraoslylceramide). The sialic acid recognition site may be masked bycis interactions with sialic acids on the same cell surface. In the immune response, may act as an inhibitory receptorupon ligand induced tyrosine phosphorylation by recruiting cytoplasmic phosphatase(s) via their SH2 domain(s) thatblock signal transduction through dephosphorylation of signaling molecules. Mediates inhibition of natural killercells cytotoxicity. May play a role in hemopoiesis. Inhibits differentiation of CD34+ cell precursors towardsmyelomonocytic cell lineage and proliferation of leukemic myeloid cells (in vitro)

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Siglec-7/CD328
Antibody (194211) [Dy ...
FAB11381E
Siglec-7/CD328 Antibody (194211) [DyLight 405]
Species: Hu
Applications: Flow, CyTOF-ready

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Bioinformatics

Gene Symbol SIGLEC7