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Siglec-1/CD169 Antibody

Images

 
Immunohistochemistry-Paraffin: Siglec-1/CD169 Antibody [NBP2-30903] - Staining of human placenta shows strong membranous positivity in Hofbauer cells.
Immunohistochemistry-Paraffin: Siglec-1/CD169 Antibody [NBP2-30903] - Staining of human lung shows strong membranous positivity in macrophages.
Immunohistochemistry-Paraffin: Siglec-1/CD169 Antibody [NBP2-30903] - Staining of human liver shows strong membranous positivity in Kupffer cells.
Immunohistochemistry-Paraffin: Siglec-1/CD169 Antibody [NBP2-30903] - Staining of human pancreas shows no positivity in exocrine glandular cells as expected.

Product Details

Summary
Reactivity HuSpecies Glossary
Applications IHC, Dual ISH-IHC
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated

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Siglec-1/CD169 Antibody Summary

Immunogen
This antibody was developed against a recombinant protein corresponding to amino acids: CTAQNLLGSISTIGRLQVEGARVVAEPGLDVPEGAALNLSCRLLGGPGPVGNSTFAWFWNDRRLHAEPVPTLAFTHVARAQAGMYH
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
SIGLEC1
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Dual RNAscope ISH-IHC Reported in (PMID: 30930117)
  • Immunohistochemistry 1:200 - 1:500
  • Immunohistochemistry-Paraffin 1:200 - 1:500
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.
Control Peptide
Siglec-1/CD169 Protein (NBP2-30903PEP)
Publications
Read Publications using
NBP2-30903 in the following applications:

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.2) and 40% Glycerol
Preservative
0.02% Sodium Azide
Purity
Immunogen affinity purified

Alternate Names for Siglec-1/CD169 Antibody

  • CD169
  • FLJ00051
  • sialic acid binding Ig-like lectin 1, sialoadhesin
  • sialoadhesin
  • Siglec1
  • Siglec-1

Background

The siglecs are a family of membrane bound lectins (of the immunoglobulin superfamily) that bind sialic acid and mediate cell-cell interactions. Family members include sialoadhesin, CD22 and CD33. Sialoadhesin is a macrophage-specific cell adhesion molecule that is expressed on activated macrophages in chronic inflammation and in tumours.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for Siglec-1/CD169 Antibody (NBP2-30903)(2)

We have publications tested in 2 confirmed species: Human, Mouse.

We have publications tested in 2 applications: Dual ISH-IHC, IHC-P.


Filter By Application
Dual ISH-IHC
(2)
IHC-P
(1)
All Applications
Filter By Species
Human
(1)
Mouse
(1)
All Species

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Secondary Antibodies

 

Isotype Controls

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Bioinformatics

Gene Symbol SIGLEC1
Uniprot