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Siglec-1/CD169 Antibody (HSn 7D2) [FITC]

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Product Details

Summary
Reactivity Hu, Mu, Po, V-ViSpecies Glossary
Applications WB, ELISA, Flow, Func, ICC/IF, IHC
Clone
HSn 7D2
Clonality
Monoclonal
Host
Mouse
Conjugate
FITC

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price
Alexa Fluor 350
NB600-534AF350
Alexa Fluor 405
NB600-534AF405
Alexa Fluor 488
NB600-534AF488
Alexa Fluor 532
NB600-534AF532
Alexa Fluor 594
NB600-534AF594
Alexa Fluor 647
NB600-534AF647
Alexa Fluor 700
NB600-534AF700
Alexa Fluor 750
NB600-534AF750
Allophycocyanin
NB600-534APC
Allophycocyanin/Cy7
NB600-534APCCY7
Biotin
NB600-534B
CoraFluor 1
NB600-534CL1
DyLight 350
NB600-534UV
DyLight 405
NB600-534V
DyLight 488
NB600-534G
DyLight 550
NB600-534R
DyLight 594
NB600-534DL594
DyLight 650
NB600-534C
DyLight 680
NB600-534FR
DyLight 755
NB600-534IR
HRP
NB600-534H
Janelia Fluor 525
NB600-534JF525
Janelia Fluor 549
NB600-534JF549
Janelia Fluor 585
NB600-534JF585
Janelia Fluor 635
NB600-534JF635
Janelia Fluor 646
NB600-534JF646
Janelia Fluor 669
NB600-534JF669
PE
NB600-534PE
PE/Atto594
NB600-534PEATT594
PE/Cy5.5
NB600-534PECY55
PE/Cy7
NB600-534PECY7
PerCP
NB600-534PCP
Unconjugated
NB600-534
mFluor Violet 450 SE
NB600-534MFV450
mFluor Violet 500 SE
NB600-534MFV500
mFluor Violet 610 SE
NB600-534MFV610
View Available Formulations
Catalog# & Formulation Size Price
Standard Formulation
NB600-534
BSA Free
NB600-534
BSA Free
NB600-534SS
Azide and BSA Free
NBP2-80947
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Siglec-1/CD169 Antibody (HSn 7D2) [FITC] Summary

Immunogen
Full-length purified human Sialoadhesin (d1-4)Fc protein. [Swiss-Prot# Q9BZZ2]
Epitope
Within domains 1-4.
Localization
Isoform 1: Cell membrane; Single-pass type I membrane protein. Isoform 2: Secreted.
Isotype
IgG1
Clonality
Monoclonal
Host
Mouse
Gene
SIGLEC1
Purity
Protein G purified
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Applications/Dilutions

Dilutions
  • ELISA
  • Flow Cytometry
  • Immunocytochemistry/ Immunofluorescence
  • Immunohistochemistry
  • Immunohistochemistry-Frozen
  • Immunohistochemistry-Paraffin
  • In vitro assay
  • In vivo assay
  • Radioimmunoassay
  • Western Blot
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Reactivity Notes

Porcine reactivity reported in scientific literature (PMID: 27441395). Mouse reactivity reported in scientific literature. Not yet tested in other species. Use in Virus reported in scientific literature (PMID:27487279).

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
PBS
Preservative
0.05% Sodium Azide
Purity
Protein G purified

Notes

This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.

Alternate Names for Siglec-1/CD169 Antibody (HSn 7D2) [FITC]

  • CD169
  • FLJ00051
  • sialic acid binding Ig-like lectin 1, sialoadhesin
  • sialoadhesin
  • Siglec1
  • Siglec-1

Background

Sialoadhesin, also known as sialic acid-binding Ig-like lectin 1, siglec-1, CD169, SIGLEC1, and SN, is a member of the sialic acid binding Ig-like lectin (SIGLEC) family. The SIGLECs are a family of membrane bound lectins that belong to the immunoglobulin superfamily. SIGLECs bind sialic acid and mediate cell to cell interactions. Family members include sialoadhesin, CD22 and CD33. Sialoadhesin is a lectin-like macrophage-specific cell adhesion molecule that mediates sialic acid dependent binding of glycoconjugate ligands on activated macrophages, lymphocytes, granulocytes, monocytes, natural killer cells, B-cells and CD8 T-cells. The Sialoadhesin protein is found in two locations within the cell, the cell membrane (isoform 1) and secreted in the cytoplasm (isoform 2). Sialoadhesin is expressed in spleen, lymph node, brain, bone marrow, liver, colon and lung tissues and in inflammatory macrophages in rheumatoid arthritis.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Siglec-1/CD169
Antibody (HSn 7D2) [F ...
NB600-534F
Siglec-1/CD169 Antibody (HSn 7D2) [FITC]
Species: Hu, Mu, Po, V-Vi
Applications: WB, ELISA, Flow, Func, ICC/IF, IHC

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Bioinformatics

Gene Symbol SIGLEC1