Name: Recombinant Human IL-1ra/IL-1F3 Protein
Brand: Novus Biologicals
SKU: 280-RA
Price: 351 USD

- COVID-19 Research Tools
  
  Antibodies
  Primary Antibodies
  Conjugated Antibodies
  
  Sample Size Antibodies
  
  KO Validated Antibodies
  
  Recombinant Antibodies
  
  Antibody Sampler Packs
  
  Antibody Pairs
  
  Secondary Antibodies
  
  Isotype Control Antibodies
  
  Proteins and Peptides
  Peptides & Proteins
  
  Blocking Peptides
  
  Biologically Active Proteins
  
  Lysates and Cell Lines
  Lysates
  
  Stem Cell Lines
- Kits
  Antibody Labeling Kits
  
  ChIP Kits
  
  ELISA Kits
  
  Flow Cytometry Kits
  
  Activators and Inhibitors
  Inhibitors
  
  Activators
  
  Support Products
  Exosome Isolation
  
  Flow Cytometry Beads
  
  IHC Tissue Slides
  
  IHC Microarrays
  
  Western Blot Gels & Buffers
  
  Western Blot Membranes
  
  All Support Products
  
  Bulk and Custom
Products
Our Protocols
- Resources
  Protocols
  
  Video Protocols
  
  Troubleshooting Guides
  
  Posters and Literature
  
  Handbooks and Guides
  
  Calculators
  
  FAQs
  
  Blogs
  
  Diseases
  
  Whitepapers
  
  Antibody Concierge
  
  Webinars
- Tools
  Spectra Viewer
  
  Flow Cytometry Panel Builder
  
  Application
  ELISA
  
  Flow Cytometry
  
  Mass Cytometry (CyTOF)
  
  ICC
  
  IHC
  
  Western Blotting
  
  Interviews
  Faculty
  
  Postdoc
Resources
View Pathways
- By Research Area
  Apoptosis
  
  Autophagy
  
  Cancer
  
  Cell Biology
  
  Cellular Markers
  
  Epigenetics
  
  Epitope Tags
  
  Exosomes Research
  
  Hypoxia
  
  Immunology
  
  Microbiology
  
  Neuroscience
  
  Stem Cells
- By Pathway
  AKT
  
  Apoptosis
  
  Autophagy
  
  ERK1/2/5 Pathway
  
  Hedgehog
  
  Hippo
  
  JNK Pathway
  
  mTOR
  
  Necroptosis
  
  NFKB Signaling
  
  p38 Signaling
  
  TGF Beta
  
  TLR
Research Areas
Get Rewards
- Customer Care
  100% Guarantee
  
  Risk Free Testing
  
  Novus Rewards Program
  
  Publication Rewards Program
  
  New Lab Discount
  
  Scholarship
  
  Travel Grants
  
  Promotions
Customer Care
Novus Careers
- About us
  Careers
  
  Collaborations
  
  Events
  
  Novus Story
  
  Our Team
  
  Philanthropy
  
  Press Releases
  
  Why choose Novus
About Us
- Contact Us
  Customer Service
  
  Distributors
  
  Technical Support
Contact

At	=	A. thaliana	SyHa	=	Golden Syrian Hamster
All	=	All Species	Ha	=	Hamster
An	=	Animal	Hu	=	Human
ArHa	=	Armenian Hamster	I	=	Insect
Av	=	Avian	Ll	=	Llama
Bb	=	Baboon	Ma	=	Mammal
Ba	=	Bacteria	Mk	=	Monkey
Bv	=	Bovine	Mu	=	Mouse
Ca	=	Canine	Multi	=	Multi-species
Ce	=	C. Elegans	NA	=	Non-species specific
Ch	=	Chicken	Or	=	Orangutan
ChHa	=	Chinese Hamster	Pl	=	Plant
Cm	=	Cynomolgus Monkey	Pm	=	Primate
Do	=	Donkey	Po	=	Porcine
Dr	=	Drosophilia	Rb	=	Rabbit
Ec	=	E. Coli	Rt	=	Rat
Eq	=	Equine	RM	=	Rhesus Macaque
Fe	=	Feline	Sh	=	Sheep
Ft	=	Ferret	Vb	=	Vertebrate
Fi	=	Fish	Vi	=	Virus
Fu	=	Fungi	Xp	=	Xenopus
Ge	=	Gerbil	Ye	=	Yeast
GP	=	Guinea Pig	Ze	=	Zebrafish
Gt	=	Goat

Reactivity	HuSpecies Glossary
Applications	Bioactivity

Catalog# & Formulation	Size	Price
Carrier Free 280-RA-010/CF

Carrier Free 280-RA-050/CF

Details of Functionality	Measured by its ability to inhibit IL-1 alpha -dependent proliferation in D10.G4.1 mouse helper T cells. Symons, J.A. et al. (1987) in Lymphokines and Interferons, a Practical Approach. Clemens, M.J. et al. (eds): IRL Press. 272. The ED₅₀ for this effect is 5-40 ng/mL in the presence of 50 pg/mL of rhIL-1 alpha .
Source	E. coli-derived human IL-1ra/IL-1F3 protein
Accession #	P18510
Protein/Peptide Type	Recombinant Proteins
Gene	IL1RN
Purity	>97%, by SDS-PAGE under reducing conditions and visualized by silver stain.
Endotoxin Note	<0.10 EU per 1 μg of the protein by the LAL method.

Storage	Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 3 months, -20 to -70 °C under sterile conditions after reconstitution.
Buffer	Lyophilized from a 0.2 μm filtered solution in PBS with BSA as a carrier protein.
Purity	>97%, by SDS-PAGE under reducing conditions and visualized by silver stain.
Reconstitution Instructions	Reconstitute at 100 μg/mL in sterile PBS containing at least 0.1% human or bovine serum albumin.

Recombinant Human IL-1ra/IL-1F3 Protein

Species Glossary

Images

Product Details

Order Details

Recombinant Human IL-1ra/IL-1F3 Protein Summary

Applications/Dilutions

Packaging, Storage & Formulations

Notes

Alternate Names for Recombinant Human IL-1ra/IL-1F3 Protein

Background

Customers Who Viewed This Item Also Viewed...

Publications for IL-1ra/IL-1F3/IL1RN (280-RA)(56)

Reviews for IL-1ra/IL-1F3/IL1RN (280-RA) (0)

FAQs for IL-1ra/IL-1F3/IL1RN (280-RA) (0)

Additional IL-1ra/IL-1F3/IL1RN Products

Blogs on IL-1ra/IL-1F3/IL1RN

Customers Who Bought This Also Bought

Contact Information

Product PDFs

Calculators

Review this Product

Bioinformatics

Publications using 280-RA	Applications	Species
Ormazabal, ME;Pavan, E;Vaena, E;Ferino, D;Biasizzo, J;Mucci, JM;Serra, F;Cifù, A;Scarpa, M;Rozenfeld, PA;Dardis, AE; Exploring the Pathophysiologic Cascade Leading to Osteoclastogenic Activation in Gaucher Disease Monocytes Generated via CRISPR/Cas9 Technology International journal of molecular sciences 2023-07-07 [PMID: 37446383] (Bioassay, Human)	Bioassay	Human
Newman, S;Wilson, B;Mamerow, D;Wollant, B;Nyein, H;Rosenberg-Hasson, Y;Maecker, H;Eisenstein, M;Soh, H; Extending the dynamic range of biomarker quantification through molecular equalization bioRxiv 2023-01-01 [PMID: 37443317] (Bioassay, Human)	Bioassay	Human
VE Morrison, MG Houpert, JB Trapani, AA Brockman, PJ Kingsley, KA Katdare, HM Layden, G Nguena-Jon, AJ Trevisan, KA Maguire-Ze, LJ Marnett, GJ Bixa, RA Ihrie, BD Carter Jedi-1/MEGF12-mediated phagocytosis controls the pro-neurogenic properties of microglia in the ventricular-subventricular zone bioRxiv : the preprint server for biology, 2023-03-06;0(0):. 2023-03-06 [PMID: 36945622] (Bioassay, Mouse)	Bioassay	Mouse
MA Kolganova, EV Melnik, EN Fisher, VV Smirnov, AM Vlasov, VI Gegechkori, NA Shulga, IE Shokhin, GV Ramenskaya Affinity Capture Elution (ACE) ELISA Method Development and Validation for Novel RPH-104 Drug Immunogenicity Evaluation Biomedicines, 2022-10-29;10(11):. 2022-10-29 [PMID: 36359270] (ELISA (Control), N/A)	ELISA (Control)	N/A
NL Cluny, KD Nyuyki, W Almishri, L Griffin, BH Lee, SA Hirota, QJ Pittman, MG Swain, KA Sharkey Recruitment of alpha4beta7 monocytes and neutrophils to the brain in experimental colitis is associated with elevated cytokines and anxiety-like behavior Journal of Neuroinflammation, 2022-04-04;19(1):73. 2022-04-04 [PMID: 35379260] (Bioassay, Mouse)	Bioassay	Mouse
K Bernau, JP Leet, H Floerke, EM Bruhn, AL Noll, IS McDermott, S Esnault, NN Jarjour, N Sandbo Interleukin-1&alpha Is a Critical Mediator of the Response of Human Bronchial Fibroblasts to Eosinophilic Inflammation Cells, 2021-03-02;10(3):. 2021-03-02 [PMID: 33801398] (Bioassay, Human)	Bioassay	Human
HC Dahl, M Kanchwala, SE Thomas-Jar, A Sandhu, P Kanumuri, AF Nawas, C Xing, C Lin, DE Frigo, NA Delk Chronic IL-1 exposure drives LNCaP cells to evolve androgen and AR independence PLoS ONE, 2020-12-16;15(12):e0242970. 2020-12-16 [PMID: 33326447] (Cell Culture, Human)	Cell Culture	Human
YC Fan, KD Lee, YC Tsai Roles of Interleukin-1 Receptor Antagonist in Prostate Cancer Progression Biomedicines, 2020-12-13;8(12):. 2020-12-13 [PMID: 33322099] (Cell Culture, Human)	Cell Culture	Human
F Namai, S Shigemori, T Ogita, T Sato, T Shimosato Microbial therapeutics for acute colitis based on genetically modified Lactococcus lactis hypersecreting IL-1Ra in mice Exp Mol Med, 2020-09-28;0(0):. 2020-09-28 [PMID: 32989233] (Bioassay, Mouse)	Bioassay	Mouse
IN Mohamed, N Sheibani, AB El-Remessy Deletion of Thioredoxin-Interacting Protein (TXNIP) Abrogates High Fat Diet-induced Retinal Leukostasis, Barrier Dysfunction and Microvascular Degeneration in a Mouse Obesity Model Int J Mol Sci, 2020-06-01;21(11):. 2020-06-01 [PMID: 32492941] (Bioassay, Human)	Bioassay	Human
Y Chen, Z Yang, B Deng, D Wu, Y Quan, Z Min Interleukin 1&beta/1RA axis in colorectal cancer regulates tumor invasion, proliferation and apoptosis via autophagy Oncol. Rep., 2020-01-22;43(3):908-918. 2020-01-22 [PMID: 32020215] (Cell Culture, Human)	Cell Culture	Human
NE Murugina, AS Budikhina, YA Dagil, PV Maximchik, LS Balyasova, VV Murugin, MV Melnikov, VS Sharova, AM Nikolaeva, GZ Chkadua, BV Pinegin, MV Pashenkov Glycolytic reprogramming of macrophages activated by NOD1 and TLR4 agonists: no association with proinflammatory cytokine production in normoxia J. Biol. Chem., 2020-01-31;0(0):. 2020-01-31 [PMID: 32005665] (Bioassay, Human)	Bioassay	Human
JS Hook, M Cao, K Weng, N Kinnare, JG Moreland Mycobacterium tuberculosis Lipoarabinomannan Activates Human Neutrophils via a TLR2/1 Mechanism Distinct from Pam3CSK4 J. Immunol., 2019-12-23;0(0):. 2019-12-23 [PMID: 31871022] (ELISA Standard, Human)	ELISA Standard	Human
L Messerschm, S Fischer, P Wiedemann, A Bringmann, M Hollborn Osmotic induction of cyclooxygenase-2 in RPE cells: Stimulation of inflammasome activation Mol. Vis., 2019-06-30;25(0):329-344. 2019-06-30 [PMID: 31341381] (Bioassay, Human)	Bioassay	Human
A Lindblad, K Persson, I Demirel IL-1RA is part of the inflammasome-regulated immune response in bladder epithelial cells and influences colonization of uropathogenic E. coli Cytokine, 2019-07-09;123(0):154772. 2019-07-09 [PMID: 31299415] (Bioassay, Human)	Bioassay	Human
L Samelko, MS Caicedo, J Jacobs, NJ Hallab Transition from metal-DTH resistance to susceptibility is facilitated by NLRP3 inflammasome signaling induced Th17 reactivity: Implications for orthopedic implants PLoS ONE, 2019-01-17;14(1):e0210336. 2019-01-17 [PMID: 30653583] (Bioassay, Human)	Bioassay	Human
K Kinnunen, N Piippo, S Loukovaara, M Hytti, K Kaarnirant, A Kauppinen Lysosomal destabilization activates the NLRP3 inflammasome in human umbilical vein endothelial cells (HUVECs) J Cell Commun Signal, 2017-05-25;0(0):. 2017-05-25 [PMID: 28547650] (Bioassay, Human)	Bioassay	Human
N Nishijima, T Hirai, K Misato, M Aoyama, E Kuroda, KJ Ishii, K Higashisak, Y Yoshioka, Y Tsutsumi Human Scavenger Receptor A1-Mediated Inflammatory Response to Silica Particle Exposure Is Size Specific Front Immunol, 2017-04-03;8(0):379. 2017-04-03 [PMID: 28421077] (Bioassay, Human)	Bioassay	Human
Y Song, Y Wang, Y Zhang, W Geng, W Liu, Y Gao, S Li, K Wang, X Wu, L Kang, C Yang Advanced glycation end products regulate anabolic and catabolic activities via NLRP3-inflammasome activation in human nucleus pulposus cells J. Cell. Mol. Med, 2017-02-22;0(0):. 2017-02-22 [PMID: 28224704] (Bioassay, Human)	Bioassay	Human
Mihai G Netea A Functional Genomics Approach to Understand Variation in Cytokine Production in Humans Cell, 2016-11-03;167(4):1099-1110.e14. 2016-11-03 [PMID: 27814507] (Bioassay, Human)	Bioassay	Human
Tissue factor is induced by interleukin-33 in human endothelial cells: a new link between coagulation and inflammation Sci Rep, 2016-05-04;6(0):25171. 2016-05-04 [PMID: 27142573] (Bioassay, Human)	Bioassay	Human
Sun Y, Zhu D, Wang G, Wang D, Zhou H, Liu X, Jiang M, Liao L, Zhou Z, Hu J Pro-Inflammatory Cytokine IL-1beta Up-Regulates CXC Chemokine Receptor 4 via Notch and ERK Signaling Pathways in Tongue Squamous Cell Carcinoma. PLoS ONE, 2015-07-15;10(7):e0132677. 2015-07-15 [PMID: 26176534] (Bioassay, Human)	Bioassay	Human
Larena M, Holmgren J, Lebens M, Terrinoni M, Lundgren A Cholera toxin, and the related nontoxic adjuvants mmCT and dmLT, promote human Th17 responses via cyclic AMP-protein kinase A and inflammasome-dependent IL-1 signaling. J Immunol, 2015-03-18;194(8):3829-39. 2015-03-18 [PMID: 25786687] (Bioassay, Human)	Bioassay	Human
Tsai C, Liong K, Gunalan M, Li N, Lim D, Fisher D, Macary P, Leo Y, Wong S, Puan K, Wong S Type I IFNs and IL-18 regulate the antiviral response of primary human gammadelta T cells against dendritic cells infected with Dengue virus. J Immunol, 2015-03-02;194(8):3890-900. 2015-03-02 [PMID: 25732728] (Bioassay, Human)	Bioassay	Human
Delaloye J, Filali-Mouhim A, Cameron M, Haddad E, Harari A, Goulet J, Gomez C, Perdiguero B, Esteban M, Pantaleo G, Roger T, Sekaly R, Calandra T Interleukin-1- and type I interferon-dependent enhanced immunogenicity of an NYVAC-HIV-1 Env-Gag-Pol-Nef vaccine vector with dual deletions of type I and type II interferon-binding proteins. J Virol, 2015-01-21;89(7):3819-32. 2015-01-21 [PMID: 25609807] (Bioassay, Human)	Bioassay	Human
Sugita S, Kamao H, Iwasaki Y, Okamoto S, Hashiguchi T, Iseki K, Hayashi N, Mandai M, Takahashi M Inhibition of T-cell activation by retinal pigment epithelial cells derived from induced pluripotent stem cells. Invest Ophthalmol Vis Sci, 2015-01-20;56(2):1051-62. 2015-01-20 [PMID: 25604685] (Bioassay, Human)	Bioassay	Human
Yan X, Jiang E, Weng H Activation of toll like receptor 4 attenuates GABA synthesis and postsynaptic GABA receptor activities in the spinal dorsal horn via releasing interleukin-1 beta. J Neuroinflammation, 2015-01-09;12(0):222. 2015-01-09 [PMID: 25571780] (Bioassay, Mouse)	Bioassay	Mouse
Foucher E, Blanchard S, Preisser L, Descamps P, Ifrah N, Delneste Y, Jeannin P IL-34- and M-CSF-induced macrophages switch memory T cells into Th17 cells via membrane IL-1alpha. Eur J Immunol, 2015-01-19;45(4):1092-102. 2015-01-19 [PMID: 25545357] (Bioassay, Human)	Bioassay	Human
Lee J, Heur M Interleukin-1beta-induced Wnt5a enhances human corneal endothelial cell migration through regulation of Cdc42 and RhoA. Mol Cell Biol, 2014-07-14;34(18):3535-45. 2014-07-14 [PMID: 25022753] (Bioassay, Human)	Bioassay	Human
Stojkovic S, Kaun C, Heinz M, Krychtiuk K, Rauscher S, Lemberger C, de Martin R, Groger M, Petzelbauer P, Huk I, Huber K, Wojta J, Demyanets S Interleukin-33 induces urokinase in human endothelial cells--possible impact on angiogenesis. J Thromb Haemost, 2014-06-01;12(6):948-57. 2014-06-01 [PMID: 24702774] (Bioassay, Human)	Bioassay	Human
Issafras H, Corbin J, Goldfine I, Roell M Detailed mechanistic analysis of gevokizumab, an allosteric anti-IL-1beta antibody with differential receptor-modulating properties. J Pharmacol Exp Ther, 2013-11-05;348(1):202-15. 2013-11-05 [PMID: 24194526] (Binding Assay)	Binding Assay
Suwara M, Green N, Borthwick L, Mann J, Mayer-Barber K, Barron L, Corris P, Farrow S, Wynn T, Fisher A, Mann D IL-1alpha released from damaged epithelial cells is sufficient and essential to trigger inflammatory responses in human lung fibroblasts. Mucosal Immunol, 2013-10-30;7(3):684-93. 2013-10-30 [PMID: 24172847] (Bioassay, Human)	Bioassay	Human
Valcarcel M, Carrascal T, Crende O, Vidal-Vanaclocha F IL-18 regulates melanoma VLA-4 integrin activation through a Hierarchized sequence of inflammatory factors. J Invest Dermatol, 2013-08-12;134(2):470-80. 2013-08-12 [PMID: 23938462] (Bioassay, Human)	Bioassay	Human
Kinoshita H, Hirata Y, Nakagawa H, Sakamoto K, Hayakawa Y, Takahashi R, Nakata W, Sakitani K, Serizawa T, Hikiba Y, Akanuma M, Shibata W, Maeda S, Koike K Interleukin-6 mediates epithelial-stromal interactions and promotes gastric tumorigenesis. PLoS ONE, 2013-04-12;8(4):e60914. 2013-04-12 [PMID: 23593346] (Bioassay, Human)	Bioassay	Human
Corvaisier M, Delneste Y, Jeanvoine H, Preisser L, Blanchard S, Garo E, Hoppe E, Barre B, Audran M, Bouvard B, Saint-Andre J, Jeannin P IL-26 Is Overexpressed in Rheumatoid Arthritis and Induces Proinflammatory Cytokine Production and Th17 Cell Generation. PLoS Biol, 2012-09-25;10(9):e1001395. 2012-09-25 [PMID: 23055831] (Bioassay, Human)	Bioassay	Human
Serelli-Lee V, Ling KL, Ho C, Yeong LH, Lim GK, Ho B, Wong SB Persistent Helicobacter pylori Specific Th17 Responses in Patients with Past H. pylori Infection Are Associated with Elevated Gastric Mucosal IL-1ÃŽÂ². PLoS ONE, 2012-06-25;7(6):e39199. 2012-06-25 [PMID: 22761739] (Bioassay, Human)	Bioassay	Human
Schipper HS, De Jager W, van Dijk ME, Meerding J, Zelissen PM, Adan RA, Prakken BJ, Kalkhoven E A multiplex immunoassay for human adipokine profiling. Clin. Chem., 2010-06-08;56(0):1320. 2010-06-08 [PMID: 20530731] (ELISA (Standard))	ELISA (Standard)
Lee WW, Kang SW, Choi J Regulating human Th17 cells via differential expression of IL-1 receptor. Blood, 2009-11-12;115(3):530-40. 2009-11-12 [PMID: 19965648] (Bioassay, Human)	Bioassay	Human
Marotta DM, Costa R, Motta EM, Fernandes ES, Medeiros R, Quintao NL, Campos MM, Calixto JB Mechanisms underlying the nociceptive responses induced by platelet-activating factor (PAF) in the rat paw. Biochem. Pharmacol., 2009-04-01;77(7):1223-35. 2009-04-01 [PMID: 19283893] (In Vivo, Rat)	In Vivo	Rat
Man PS, Lawrence CB Interleukin-1 mediates the anorexic and febrile actions of galanin-like Peptide. Endocrinology, 2008-07-10;149(11):5791-802. 2008-07-10 [PMID: 18617619] (In Vivo, Rat)	In Vivo	Rat
Wilson HL, Varcoe RW, Stokes L, Holland KL, Francis SE, Dower SK, Surprenant A, Crossman DC P2X receptor characterization and IL-1/IL-1Ra release from human endothelial cells. Br. J. Pharmacol., 2007-03-12;151(1):115-27. 2007-03-12 [PMID: 17351655] (Bioassay, Western Blot, Human)	Bioassay, Western Blot	Human
Fitzgerald DC, Meade KG, McEvoy AN, Lillis L, Murphy EP, Machugh DE, Baird AW Tumour necrosis factor-alpha (TNF-alpha) increases nuclear factor kappaB (NFkappaB) activity in and interleukin-8 (IL-8) release from bovine mammary epithelial cells. Vet. Immunol. Immunopathol., 2007-01-09;116(1):59-68. 2007-01-09 [PMID: 17276517] (Bioassay, Bovine)	Bioassay	Bovine
Maedler K, Schumann DM, Sauter N, Ellingsgaard H, Bosco D, Baertschiger R, Iwakura Y, Oberholzer J, Wollheim CB, Gauthier BR, Donath MY Low concentration of interleukin-1beta induces FLICE-inhibitory protein-mediated beta-cell proliferation in human pancreatic islets. Diabetes, 2006-10-01;55(10):2713-22. 2006-10-01 [PMID: 17003335] (Bioassay, Human)	Bioassay	Human
Peng H, Erdmann N, Whitney N, Dou H, Gorantla S, Gendelman HE, Ghorpade A, Zheng J HIV-1-infected and/or immune activated macrophages regulate astrocyte SDF-1 production through IL-1beta. Glia, 2006-11-01;54(6):619-29. 2006-11-01 [PMID: 16944452] (Bioassay, Human)	Bioassay	Human
Hatfield K, Ryningen A, Corbascio M, Bruserud O Microvascular endothelial cells increase proliferation and inhibit apoptosis of native human acute myelogenous leukemia blasts. Int. J. Cancer, 2006-11-15;119(10):2313-21. 2006-11-15 [PMID: 16921487] (Bioassay, Human)	Bioassay	Human
Janes KA, Gaudet S, Albeck JG, Nielsen UB, Lauffenburger DA, Sorger PK The response of human epithelial cells to TNF involves an inducible autocrine cascade. Cell, 2006-03-24;124(6):1225-39. 2006-03-24 [PMID: 16564013] (Bioassay, Human)	Bioassay	Human
Kao CY, Chen Y, Thai P, Wachi S, Huang F, Kim C, Harper RW, Wu R IL-17 markedly up-regulates beta-defensin-2 expression in human airway epithelium via JAK and NF-kappaB signaling pathways. J. Immunol., 2004-09-01;173(5):3482-91. 2004-09-01 [PMID: 15322213] (Bioassay, Human)	Bioassay	Human
Wolk K, Kunz S, Witte E, Friedrich M, Asadullah K, Sabat R IL-22 increases the innate immunity of tissues. Immunity, 2004-08-01;21(2):241-54. 2004-08-01 [PMID: 15308104] (Bioassay, Human)	Bioassay	Human
Morita K, Miyasako T, Kitayama S, Dohi T Interleukin-1 inhibits voltage-dependent P/Q-type Ca2+ channel associated with the inhibition of the rise of intracellular free Ca2+ concentration and catecholamine release in adrenal chromaffin cells. Biochim. Biophys. Acta, 2004-08-04;1673(3):160-9. 2004-08-04 [PMID: 15279887] (Bioassay, Bovine)	Bioassay	Bovine
Kawano Y, Fukuda J, Itoh H, Takai N, Nasu K, Miyakawa I The effect of inflammatory cytokines on secretion of macrophage colony-stimulating factor and monocyte chemoattractant protein-1 in human granulosa cells. Am. J. Reprod. Immunol., 2004-08-01;52(2):124-8. 2004-08-01 [PMID: 15274652] (Bioassay, Human)	Bioassay	Human
Copeland S, Siddiqui J, Remick D Direct comparison of traditional ELISAs and membrane protein arrays for detection and quantification of human cytokines. J. Immunol. Methods, 2004-01-01;284(1):99-106. 2004-01-01 [PMID: 14736420] (ELISA (Standard))	ELISA (Standard)
Liu R, Liote F, Rose DM, Merz D, Terkeltaub R Proline-rich tyrosine kinase 2 and Src kinase signaling transduce monosodium urate crystal-induced nitric oxide production and matrix metalloproteinase 3 expression in chondrocytes. Arthritis Rheum., 2004-01-01;50(1):247-58. 2004-01-01 [PMID: 14730623] (Bioassay, Bovine)	Bioassay	Bovine
Schaub FJ, Liles WC, Ferri N, Sayson K, Seifert RA, Bowen-Pope DF Fas and Fas-associated death domain protein regulate monocyte chemoattractant protein-1 expression by human smooth muscle cells through caspase- and calpain-dependent release of interleukin-1alpha. Circ. Res., 2003-08-28;93(6):515-22. 2003-08-28 [PMID: 12946945] (Bioassay, Human)	Bioassay	Human
Park JS, 107290, Kim YS, Jee YK, Myong NH, Lee KY Interleukin-8 production in tuberculous pleurisy: role of mesothelial cells stimulated by cytokine network involving tumour necrosis factor-alpha and interleukin-1 beta. Active immunotherapy against pathogenic Cis pT231-tau suppresses neurodegeneration in traumatic brain injury mouse models, 2003-05-01;57(5):463-9. 2003-05-01 [PMID: 12753503] (Bioassay, Human)	Bioassay	Human
Lindemann S, Å¸ùw _#Ÿ½, Tolley ND, Dixon DA, McIntyre TM, Prescott SM, Zimmerman GA, Weyrich AS Activated platelets mediate inflammatory signaling by regulated interleukin 1beta synthesis. 2001-08-06;154(3):485-90. 2001-08-06 [PMID: 11489912] (Bioassay, Human)	Bioassay	Human
Lauw FN, Dekkers PE, te Velde AA, Speelman P, Levi M, Kurimoto M, Hack CE, Van Deventer SJ, van der Poll T Interleukin-12 induces sustained activation of multiple host inflammatory mediator systems in chimpanzees. J. Infect. Dis., 1999-03-01;179(3):646-52. 1999-03-01 [PMID: 9952371] (ELISA (Standard))	ELISA (Standard)
Show All 56 Publications. Collapse Publications.

Gene Symbol	IL1RN
Uniprot	P18510()