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Rat CXCL2/CINC-3 Quantikine ELISA Kit

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Summary
Reactivity RtSpecies Glossary
Applications ELISA
Conjugate
HRP

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Rat CXCL2/CINC-3 Quantikine ELISA Kit Summary

Background
The Quantikine Rat CINC-3 Immunoassay is a 4.5 hour solid-phase ELISA designed to measure rat CINC-3 in cell culture supernates, serum, and plasma. It contains E. coli-expressed recombinant rat CINC-3 and antibodies raised against the recombinant factor. This immunoassay has been shown to accurately quantitate the recombinant factor. Results obtained using natural rat CINC-3 showed ...linear curves that were parallel to the standard curves obtained using the Quantikine kit standards. These results indicate that this kit can be used to determine relative mass values for naturally occurring rat CINC-3.
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Specificity
Natural and recombinant rat CINC-3
Source
N/A
Assay Type
Solid Phase Sandwich ELISA
Inter-Assay
See PDF Datasheet for details
Intra-Assay
See PDF Datasheet for details
Spike Recovery
See PDF Datasheet for details
Sample Volume
See PDF Datasheet for details
Gene
Cxcl2

Applications/Dilutions

Dilutions
  • ELISA
Application Notes
No significant interference observed with available related molecules.
Publications
Read Publications using RCN300.

Packaging, Storage & Formulations

Storage
Store the unopened product at 2 - 8 °C. Do not use past expiration date.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for Rat CXCL2/CINC-3 Quantikine ELISA Kit

  • chemokine (C-X-C motif) ligand 2
  • CINC-2a
  • CINC3
  • CINC-3
  • C-X-C Motif Chemokine 2
  • CXCL2
  • GRO beta
  • GRO2 oncogene
  • GRO2
  • GROB
  • Gro-beta
  • Growth-regulated protein beta
  • Macrophage inflammatory protein 2-alpha
  • melanoma growth stimulatory activity beta
  • MGSA beta
  • MGSA-b
  • MGSA-beta
  • MIP2
  • MIP-2
  • MIP2A
  • MIP-2a
  • MIP2-alpha
  • SCYB2

Background

CXCL2/GRO beta, also called MIP-2 in mouse and CINC-3 in rat, is a member of the CXC chemokine family. Human CXCL2/GRO beta is 107 amino acids (aa) in length with a predicted molecular weight of 11 kDa. The mouse and rat orthologs share 70% and 71% aa sequence identity with the human protein, respectively. N-terminal aa 1-4 of CXCL2/GRO beta can be post-translationally cleaved which confers enhanced hematopoietic bioactivity. CXCL2/GRO beta is produced by a variety of cell types including monocytes and macrophages at sites of inflammation and is chemotactic for granulocytes, including neutrophils.

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⚠ WARNING: This product can expose you to chemicals including N,N-Dimethylforamide, which is known to the State of California to cause cancer. For more information, go to www.P65Warnings.ca.gov.

Publications for CXCL2/GRO beta/MIP-2/CINC-3 (RCN300)(17)

We have publications tested in 3 confirmed species: Human, Mouse, Rat.


Filter By Application
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Human
(1)
Mouse
(1)
Rat
(15)
All Species
Showing Publications 1 - 10 of 17. Show All 17 Publications.
Publications using RCN300 Applications Species
Y Zhang, R Sang, J Bao, Z Jiang, D Qian, Y Zhou, W Su, J Wei, L Zhao, Z Wei, Y Zhao, M Shi, G Chen Schwann cell-derived CXCL2 contributes to cancer pain by modulating macrophage infiltration in a mouse breast cancer model Brain, Behavior, and Immunity, 2023-02-06;0(0):. 2023-02-06 [PMID: 36754246] (Rat) Rat
C Kang, J Kim, S Ju, S Park, JW Yoo, IS Yoon, MS Kim, Y Jung Dapsone Azo-Linked with Two Mesalazine Moieties Is a "Me-Better" Alternative to Sulfasalazine Pharmaceutics, 2022-03-21;14(3):. 2022-03-21 [PMID: 35336057] (Rat) Rat
E D'Angelo, A Koutsoukou, P Della Vall, G Gentile, M Pecchiari The development of various forms of lung injury with increasing tidal volume in normal rats Respir Physiol Neurobiol, 2020-01-03;274(0):103369. 2020-01-03 [PMID: 31911202] (Rat) Rat
S Chakrabort, S Islam, S Saha, R Ain Dexamethasone-induced Intra-Uterine Growth Restriction impacts NOSTRIN and its downstream effector genes in the rat mesometrial uterus Sci Rep, 2018-05-29;8(1):8342. 2018-05-29 [PMID: 29844445] (Human) Human
T Tomonaga, H Izumi, Y Yoshiura, T Myojo, T Oyabu, BW Lee, T Okada, Y Li, K Kawai, T Higashi, Y Morimoto Assessment of Pulmonary Toxicity Induced by Inhaled Toner with External Additives Biomed Res Int, 2017-01-16;2017(0):4245309. 2017-01-16 [PMID: 28191462] (Mouse) Mouse
Burke S, Lu D, Sparer T, Masi T, Goff M, Karlstad M, Collier J NF-kappaB and STAT1 control CXCL1 and CXCL2 gene transcription. Am J Physiol Endocrinol Metab, 2013-11-26;306(2):E131-49. 2013-11-26 [PMID: 24280128] (Rat) Rat
Ding N, Wang F, Xiao H, Xu L, She S Mechanical ventilation enhances HMGB1 expression in an LPS-induced lung injury model. PLoS ONE, 2013-09-10;8(9):e74633. 2013-09-10 [PMID: 24058610] (Rat) Rat
A short course of infusion of a hydrogen sulfide-donor attenuates endotoxemia induced organ injury via stimulation of anti-inflammatory pathways, with no additional protection from prolonged infusion. Cytokine, 2012-12-23;61(2):614-21. 2012-12-23 [PMID: 23267760] (Rat) Rat
Shiratori M, Tozaki-Saitoh H, Yoshitake M P2X7 receptor activation induces CXCL2 production in microglia through NFAT and PKC/MAPK pathways. J. Neurochem., 2010-05-13;114(3):810-9. 2010-05-13 [PMID: 20477948] (Rat) Rat
Yang S, Hu S, Chen J, Choudhry MA, Rue LW, Bland KI, Chaudry IH Mechanism of hepatoprotection in proestrus female rats following trauma-hemorrhage: heme oxygenase-1-derived normalization of hepatic inflammatory responses. J. Leukoc. Biol., 2009-02-24;85(6):1015-26. 2009-02-24 [PMID: 19244165] (Rat) Rat
Show All 17 Publications.

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Bioinformatics

Gene Symbol Cxcl2