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Rad17 [p Ser645] Antibody [Biotin]

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Product Details

Summary
Reactivity Hu, MuSpecies Glossary
Applications WB, IHC, KO
Clonality
Polyclonal
Host
Rabbit
Conjugate
Biotin

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price
Alexa Fluor 350
NB100-273AF350
Alexa Fluor 405
NB100-273AF405
Alexa Fluor 488
NB100-273AF488
Alexa Fluor 532
NB100-273AF532
Alexa Fluor 594
NB100-273AF594
Alexa Fluor 647
NB100-273AF647
Alexa Fluor 700
NB100-273AF700
Alexa Fluor 750
NB100-273AF750
Allophycocyanin
NB100-273APC
CoraFluor 1
NB100-273CL1
DyLight 350
NB100-273UV
DyLight 405
NB100-273V
DyLight 488
NB100-273G
DyLight 550
NB100-273R
DyLight 594
NB100-273DL594
DyLight 650
NB100-273C
DyLight 680
NB100-273FR
DyLight 755
NB100-273IR
FITC
NB100-273F
HRP
NB100-273H
Janelia Fluor 525
NB100-273JF525
Janelia Fluor 549
NB100-273JF549
Janelia Fluor 646
NB100-273JF646
Janelia Fluor 669
NB100-273JF669
PE
NB100-273PE
PerCP
NB100-273PCP
Unconjugated
NB100-273
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Rad17 [p Ser645] Antibody [Biotin] Summary

Immunogen
A synthetic peptide, which represented a portion of human Rad17 (LocusLink ID 5884) around serine 645.
Modification
p Ser645
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
RAD17
Purity
Immunogen affinity purified
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Applications/Dilutions

Dilutions
  • Immunohistochemistry
  • Knockout Validated
  • Western Blot
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
PBS
Preservative
0.05% Sodium Azide
Purity
Immunogen affinity purified

Notes

[PUBLIC NOTES]

Alternate Names for Rad17 [p Ser645] Antibody [Biotin]

  • CCYC
  • cell cycle checkpoint protein (RAD17)
  • cell cycle checkpoint protein RAD17
  • FLJ41520
  • HRAD17
  • R24L
  • RAD1 (S. pombe) homolog
  • RAD1 homolog
  • RAD17 homolog (S. pombe)
  • Rad17
  • Rad17-like protein
  • RAD17SP
  • RAD24
  • RF-C activator 1 homolog
  • RF-C/activator 1 homolog

Background

Signals originating from damaged DNA activate checkpoint pathways and target the mitotic apparatus via a number a distinct mechanisms. These checkpoints link damage to DNA with the components of the cell cycle through signal transduction systems. In mammals, five genes have been identified as components of DNA damage-induced checkpoint pathways: ATM, p53, p21/WAF1/CIP1, hCHK1, and 14-3-3sigma. When overexpressed in mammalian cells, hRAD17 activates p53 and causes an accumulation of G1 phase cells, suggesting an involvement of the hRAD17 gene in this checkpoint pathway.(1).

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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XPF Antibody
(OTI4E11)
NBP2-01020
Flow Cytometry XPF Antibody (OTI4E11)
Western Blot XPF Antibody (OTI4E11)
Immunohistochemistry-Paraffin XPF Antibody (OTI4E11)
Species: Hu, Mu
Applications: Flow, ICC/IF, IHC, IHC-P, WB
RFC1 Antibody
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Secondary Antibodies

 

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Bioinformatics

Gene Symbol RAD17