Quantikine Immunoassay Control Set 1000 for Human IL-1ra Summary
Additional Information |
For use with catalog numbers DRA00B, SRA00B, PDRA00B |
Source |
N/A |
Inter-Assay |
See PDF Datasheet for details |
Intra-Assay |
See PDF Datasheet for details |
Spike Recovery |
See PDF Datasheet for details |
Sample Volume |
See PDF Datasheet for details |
Gene |
IL1RN |
Applications/Dilutions
Packaging, Storage & Formulations
Storage |
Store the unopened product at 2 - 8 °C. Do not use past expiration date. |
Notes
This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.
Alternate Names for Quantikine Immunoassay Control Set 1000 for Human IL-1ra
Background
IL-1ra (IL-1 receptor antagonist) is a widely expressed acute phase protein that serves to dampen inflammation. IL-1ra binds to both IL-1 RI and IL-1 RII. It competitively inhibits IL-1 (alpha or beta) binding to IL-1 RI and does not trigger recruitment of the accessory molecule IL-1 R AcP or activation of IL-1 RI signaling. IL-1ra blocks the proinflammatory actions of IL-1 including Prostaglandin E2 and IL-6 release from endothelial cells, fever generation, thrombocytosis, the production of hepatic acute phase proteins, and neutrophil expansion and infiltration.
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