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Protein S/PROS1 Antibody (391609) [Unconjugated]

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Western blot shows human plasma. PVDF membrane was probed with 0.5 µg/mL of Mouse Anti-Human Protein S/PROS1 Monoclonal Antibody (Catalog # MAB4036) followed by HRP-conjugated Anti-Mouse IgG Secondary Antibody (Catalog # HAF018). A specific band was detected for Protein S/PROS1 at approximately 80 kDa (as indicated). This experiment was conducted under non-reducing conditions and using Immunoblot Buffer Group 1.
Western blot shows human plasma. PVDF membrane was probed with 0.5 µg/mL of Mouse Anti-Human Protein S/PROS1 Monoclonal Antibody (Catalog # MAB4036) followed by HRP-conjugated Anti-Mouse IgG Secondary Antibody (Catalog ...read more

Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB
Clone
391609
Clonality
Monoclonal
Host
Mouse
Conjugate
Unconjugated
Concentration
LYOPH

Order Details

View Available Formulations
Catalog# & Formulation Size Price
Carrier Free
MAB4036-SP
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Protein S/PROS1 Antibody (391609) [Unconjugated] Summary

Immunogen
Mouse myeloma cell line NS0-derived recombinant human Protein S
Ala42-Trp670
Accession # P07225
Specificity
Detects human Protein S in direct ELISAs and Western blots. In direct ELISAs and Western blots, this antibody does not cross‑react with recombinant mouse Protein S.
Source
N/A
Isotype
IgG1
Clonality
Monoclonal
Host
Mouse
Gene
PROS1
Purity Statement
Protein A or G purified from hybridoma culture supernatant
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.
Learn about the Innovator's Reward

Applications/Dilutions

Dilutions
  • Western Blot 0.5 ug/mL
Publications
Read Publications using
MAB4036 in the following applications:

Packaging, Storage & Formulations

Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.
Buffer
Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.
Preservative
No Preservative
Concentration
LYOPH
Reconstitution Instructions
Reconstitute at 0.5 mg/mL in sterile PBS.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for Protein S/PROS1 Antibody (391609) [Unconjugated]

  • EC 3.4.21
  • PROS
  • PROS1
  • protein S (alpha)
  • Protein S
  • protein Sa
  • PS21
  • PS22
  • PS23
  • PS24
  • PS25
  • PSA
  • vitamin K-dependent plasma protein S
  • vitamin K-dependent protein S

Background

The PROS1 gene encodes Protein S (PS), a ~70 kDa vitamin-K dependent plasma glycoprotein mainly synthesized by human hepatocytes. PS is a non-enzymatic cofactor in the degradation of coagulation factors Va and VIIIa and thus plays an anticoagulant role. Approximately 60% circulates in complex with C4b-binding protein. Free PS is a mixture of monomers and multimers. The 652 aa PS proprotein is heavily modified with 11 carboxyglutamates, one hydroxyaspartate, disulfides and glycosylation. Human Protein S shows 80% aa identity with mouse Protein S.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Protein S/PROS1
Antibody (391609) [Un ...
MAB4036
Protein S/PROS1 Antibody (391609) [Unconjugated]
Species: Hu
Applications: WB

Publications for Protein S/PROS1 Antibody (MAB4036)(2)

We have publications tested in 1 confirmed species: Human.

We have publications tested in 2 applications: ICC, Western Blot.


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Bioinformatics

Gene Symbol PROS1
Uniprot