Porcine IL-8/CXCL8 Quantikine ELISA Kit

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Interleukin-8 (IL-8), also known as CXCL8, is a chemokine that is upregulated at sites of inflammation where it promotes neutrophil infiltration and activation. IL-8 can form homodimers and heterodimers with CXCL4/PF4. Its bioactivity is regulated by proteolytic truncations, citrullination, and the decoy receptor DARC. IL-8 signals through CXCR1/IL-8 RA, which is also used by CXCL6, and through CXCR2/IL-8 RB, which is used by multiple CXC chemokines. IL-8 also binds to Serpin A1/alpha-1 Antitrypsin which prevents IL-8 interaction with CXCR1.

We have publications tested in 1 confirmed species: Porcine.

Showing Publications 1 - 10 of 34. Show All 34 Publications. Collapse Publications.

Publications using P8000	Applications	Species
Zhou, B;Xiao, K;Guo, J;Xu, Q;Xu, Q;Lv, Q;Zhu, H;Zhao, J;Liu, Y; Necroptosis contributes to the intestinal toxicity of deoxynivalenol and is mediated by methyltransferase SETDB1 Journal of hazardous materials 2024-08-05 [PMID: 38823098] (Porcine)		Porcine
JB Lee, SK Kim, D Han, JW Yoon Mutating both relA and spoT of enteropathogenic Escherichia coli E2348/69 attenuates its virulence and induces interleukin 6 in vivo Frontiers in Microbiology, 2023-03-02;14(0):1121715. 2023-03-02 [PMID: 36937293] (Porcine)		Porcine
DM Holanda, SW Kim Impacts of weaning weights and mycotoxin challenges on jejunal mucosa-associated microbiota, intestinal and systemic health, and growth performance of nursery pigs Journal of animal science and biotechnology, 2022-04-13;13(1):43. 2022-04-13 [PMID: 35413935] (Porcine)		Porcine
JX Boeckman, S Sprayberry, AM Korn, JS Suchodolsk, C Paulk, K Genovese, RR Rech, PR Giaretta, AK Blick, T Callaway, JJ Gill Effect of chronic and acute enterotoxigenic E. coli challenge on growth performance, intestinal inflammation, microbiome, and metabolome of weaned piglets Scientific Reports, 2022-03-23;12(1):5024. 2022-03-23 [PMID: 35323827] (Porcine)		Porcine
VS Michaelsen, RVP Ribeiro, E Brambate, A Ali, A Wang, L Pires, M Kawashima, Y Zhang, A Gazzalle, S Keshavjee, L Del Sorbo, M Cypel A novel pre-clinical strategy to deliver antimicrobial doses of inhaled nitric oxide PLoS ONE, 2021-10-13;16(10):e0258368. 2021-10-13 [PMID: 34644318] (Porcine)		Porcine
X Qu, C Neuhoff, MU Cinar, M Pröll, E Tholen, D Tesfaye, M Hölker, K Schellande, MJ Uddin Epigenetic Modulation of TLR4 Expression by Sulforaphane Increases Anti-Inflammatory Capacity in Porcine Monocyte-Derived Dendritic Cells Biology, 2021-05-31;10(6):. 2021-05-31 [PMID: 34072812] (Porcine)		Porcine
S Halvachiza, M Teuben, M Lempert, Y Kalbas, N Cesarovic, M Lipiski, E Benninger, P Cinelli, R Pfeifer, HC Pape Protective effects of new femoral reaming techniques (Reamer irrigator aspirator, RIA I and II) on pulmonary function and posttraumatic contusion (CT morphology) - results from a standardized large animal model Injury, 2020-10-06;0(0):. 2020-10-06 [PMID: 33046248] (Porcine)		Porcine
A Toschi, B Tugnoli, B Rossi, A Piva, E Grilli Thymol modulates the endocannabinoid system and gut chemosensing of weaning pigs BMC Vet. Res., 2020-08-12;16(1):289. 2020-08-12 [PMID: 32787931] (Porcine)		Porcine
DM Holanda, A Yiannikour, SW Kim Investigation of the Efficacy of a Postbiotic Yeast Cell Wall-Based Blend on Newly-Weaned Pigs under a Dietary Challenge of Multiple Mycotoxins with Emphasis on Deoxynivalenol Toxins (Basel), 2020-08-06;12(8):. 2020-08-06 [PMID: 32781569] (Porcine)		Porcine
S McCleary, R Strong, RR McCarthy, JC Edwards, EL Howes, LM Stevens, PJ Sánchez-Co, A Núñez, S Watson, AJ Mileham, SG Lillico, C Tait-Burka, C Proudfoot, M Ballantyne, CBA Whitelaw, F Steinbach, HR Crooke Substitution of warthog NF-kappaB motifs into RELA of domestic pigs is not sufficient to confer resilience to African swine fever virus Sci Rep, 2020-06-02;10(1):8951. 2020-06-02 [PMID: 32488046] (Porcine)		Porcine
DM Holanda, SW Kim Efficacy of Mycotoxin Detoxifiers on Health and Growth of Newly-Weaned Pigs under Chronic Dietary Challenge of Deoxynivalenol Toxins (Basel), 2020-05-09;12(5):. 2020-05-09 [PMID: 32397551] (Porcine)		Porcine
S Spring, H Premathila, U DeSilva, C Shili, S Carter, A Pezeshki Low Protein-High Carbohydrate Diets Alter Energy Balance, Gut Microbiota Composition and Blood Metabolomics Profile in Young Pigs Sci Rep, 2020-02-24;10(1):3318. 2020-02-24 [PMID: 32094453] (Porcine)		Porcine
D Desmonts d, R Moges, A Siddiq, T Allain, TD Feener, GP Muench, N McKenna, RM Yates, AG Buret Immuno-modulating properties of Tulathromycin in porcine monocyte-derived macrophages infected with porcine reproductive and respiratory syndrome virus PLoS ONE, 2019-08-23;14(8):e0221560. 2019-08-23 [PMID: 31442273] (Porcine)		Porcine
SE Pischke, S Hestenes, HT Johansen, H Fure, JF Bugge, A Espinoza, H Skulstad, T Edvardsen, E Fosse, TE Mollnes, PS Halvorsen, EW Nielsen Sepsis causes right ventricular myocardial inflammation independent of pulmonary hypertension in a porcine sepsis model PLoS ONE, 2019-06-27;14(6):e0218624. 2019-06-27 [PMID: 31247004] (Porcine)		Porcine
Y Luo, J Xu, C Zhang, C Jiang, Y Ma, H He, Y Wu, B Devriendt, E Cox, H Zhang Toll-like receptor 5-mediated IL-17C expression in intestinal epithelial cells enhances epithelial host defense against F4+ ETEC infection Vet. Res., 2019-06-20;50(1):48. 2019-06-20 [PMID: 31221216] (Porcine)		Porcine
J Hervé, E Terenina, K Haurogné, E Bacou, E Kulikova, M Allard, Y Billon, JM Bach, P Mormède, B Lieubeau Effects of divergent selection upon adrenocortical activity on immune traits in pig BMC Vet. Res., 2019-03-04;15(1):71. 2019-03-04 [PMID: 30832653] (Porcine)		Porcine
M Galasso, JJ Feld, Y Watanabe, M Pipkin, C Summers, A Ali, R Qaqish, M Chen, RVP Ribeiro, K Ramadan, L Pires, VS Bagnato, C Kurachi, V Cherepanov, G Moonen, A Gazzalle, TK Waddell, M Liu, S Keshavjee, BC Wilson, A Humar, M Cypel Inactivating hepatitis C virus in donor lungs using light therapies during normothermic ex vivo lung perfusion Nat Commun, 2019-01-29;10(1):481. 2019-01-29 [PMID: 30696822] (Porcine)		Porcine
A Bergmann, T Schilling, G Hedenstier, K Ahlgren, A Larsson, M Kretzschma, A Kozian, T Hachenberg Pulmonary Effects of Remote Ischemic Preconditioning in a Porcine Model of Ventilation-induced Lung Injury Respir Physiol Neurobiol, 2018-08-31;0(0):. 2018-08-31 [PMID: 30176289] (Porcine)		Porcine
H Yan, KM Ajuwon Butyrate modifies intestinal barrier function in IPEC-J2 cells through a selective upregulation of tight junction proteins and activation of the Akt signaling pathway PLoS ONE, 2017-06-27;12(6):e0179586. 2017-06-27 [PMID: 28654658] (Porcine)		Porcine
Yeung JC, Wagnetz D, Cypel M, Rubacha M, Koike T, Chun YM, Hu J, Waddell TK, Hwang DM, Liu M, Keshavjee S Ex vivo adenoviral vector gene delivery results in decreased vector-associated inflammation pre- and post-lung transplantation in the pig. Mol. Ther., 2012-03-27;20(6):1204-11. 2012-03-27 [PMID: 22453765] (Porcine)		Porcine
Schaefers MM, Breshears LM, Anderson MJ, Lin YC, Grill AE, Panyam J, Southern PJ, Schlievert PM, Peterson ML Epithelial proinflammatory response and curcumin-mediated protection from staphylococcal toxic shock syndrome toxin-1. PLoS ONE, 2012-03-14;7(3):e32813. 2012-03-14 [PMID: 22431984] (Porcine)		Porcine
Riboulet-Bisson E, Sturme MH, Jeffery IB Effect of Lactobacillus salivarius bacteriocin Abp118 on the mouse and pig intestinal microbiota. PLoS ONE, 2012-02-17;7(2):e31113. 2012-02-17 [PMID: 22363561] (Porcine)		Porcine
Barratt-Due A, Thorgersen EB, Lindstad JK, Pharo A, Lissina O, Lambris JD, Nunn MA, Mollnes TE Ornithodoros moubata complement inhibitor is an equally effective C5 inhibitor in pigs and humans. J. Immunol., 2011-09-30;187(9):4913-9. 2011-09-30 [PMID: 21964028] (Porcine)		Porcine
Martinez-Olondris P, Rigol M, Soy D, Guerrero L, Agusti C, Quera MA, Li Bassi G, Esperatti M, Luque N, Liapikou M, Filella X, Marco F, de la Bellacasa JP, Torres A Efficacy of linezolid compared to vancomycin in an experimental model of pneumonia induced by methicillin-resistant Staphylococcus aureus in ventilated pigs. Crit. Care Med., 2012-01-01;40(1):162-8. 2012-01-01 [PMID: 21926613] (Porcine)		Porcine
Hellerud BC, Nielsen EW, Thorgersen EB, Lindstad JK, Pharo A, Tonnessen TI, Castellheim A, Mollnes TE, Brandtzaeg P Dissecting the effects of lipopolysaccharides from nonlipopolysaccharide molecules in experimental porcine meningococcal sepsis. Crit. Care Med., 2010-06-01;38(6):1467-74. 2010-06-01 [PMID: 20400898] (Porcine)		Porcine
McILwain RB, Timpa JG, Kurundkar AR Plasma concentrations of inflammatory cytokines rise rapidly during ECMO-related SIRS due to the release of preformed stores in the intestine. Lab. Invest., 2009-11-09;90(1):128-39. 2009-11-09 [PMID: 19901912] (Porcine)		Porcine
Thorgersen EB, Hellerud BC, Nielsen EW, Barratt-Due A, Fure H, Lindstad JK, Pharo A, Fosse E, Tonnessen TI, Johansen HT, Castellheim A, Mollnes TE CD14 inhibition efficiently attenuates early inflammatory and hemostatic responses in Escherichia coli sepsis in pigs. FASEB J., 2009-10-19;24(3):712-22. 2009-10-19 [PMID: 19841036] (Porcine)		Porcine
Wall R, Ross RP, Shanahan F, O'Mahony L, O'Mahony C, Coakley M, Hart O, Lawlor P, Quigley EM, Kiely B, Fitzgerald GF, Stanton C Metabolic activity of the enteric microbiota influences the fatty acid composition of murine and porcine liver and adipose tissues. Am. J. Clin. Nutr., 2009-04-08;89(5):1393-401. 2009-04-08 [PMID: 19357220] (Porcine)		Porcine
Sibila O, Luna CM, Agusti C, Baquero S, Gando S, Patron JR, Morato JG, Absi R, Bassi N, Torres A Effects of glucocorticoids in ventilated piglets with severe pneumonia. Eur. Respir. J., 2008-05-28;32(4):1037-46. 2008-05-28 [PMID: 18508831] (Porcine)		Porcine
Saethre M, Schneider MK, Lambris JD, Magotti P, Haraldsen G, Seebach JD, Mollnes TE Cytokine secretion depends on Galalpha(1,3)Gal expression in a pig-to-human whole blood model. J. Immunol., 2008-05-01;180(9):6346-53. 2008-05-01 [PMID: 18424758] (Porcine)		Porcine
von Bismarck P, Wistadt CF, Klemm K, Winoto-Morbach S, Uhlig U, Schutze S, Adam D, Lachmann B, Uhlig S, Krause MF Improved pulmonary function by acid sphingomyelinase inhibition in a newborn piglet lavage model. Am. J. Respir. Crit. Care Med., 2008-02-28;177(11):1233-41. 2008-02-28 [PMID: 18310483] (Porcine)		Porcine
Sibila O, Agusti C, Torres A, Baquero S, Gando S, Patron JR, Morato JG, Goffredo DH, Bassi N, Luna CM Experimental Pseudomonas aeruginosa pneumonia: evaluation of the associated inflammatory response. Eur. Respir. J., 2007-09-05;30(6):1167-72. 2007-09-05 [PMID: 17804447] (Porcine)		Porcine
Moller S, Lauridsen C Dietary fatty acid composition rather than vitamin E supplementation influence ex vivo cytokine and eicosanoid response of porcine alveolar macrophages. Cytokine, 2006-08-17;35(1):6-12. 2006-08-17 [PMID: 16914322] (Porcine)		Porcine
Seeger FH, U£3+jV—I¬, Blessing E, Gu L, Bornhold R, Denger S, Kreuzer J Fibrinogen induces chemotactic activity in endothelial cells. 2002-10-01;176(2):109-15. 2002-10-01 [PMID: 12354170] (Porcine)		Porcine
Show All 34 Publications. Collapse Publications.

Array P8000

• CXCL8/IL-8 Antibodies
• CXCL8/IL-8 Antibody Pair
• CXCL8/IL-8 ELISA Kits
• CXCL8/IL-8 Kits
• CXCL8/IL-8 Lysate
• CXCL8/IL-8 Proteins
• CXCL8/IL-8 Proteins and Enzymes
• CXCL8/IL-8 ELISAs