Porcine IL-8/CXCL8 DuoSet ELISA, 15 Plate Summary
Source |
N/A |
Assay Type |
Solid Phase Sandwich ELISA |
Inter-Assay |
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Intra-Assay |
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Spike Recovery |
|
Sample Volume |
|
Gene |
CXCL8 |
Applications/Dilutions
Dilutions |
|
Application Notes |
No significant interference observed with available related molecules. |
Publications |
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Packaging, Storage & Formulations
Storage |
Store the unopened product at 2 - 8 °C. Do not use past expiration date. |
Notes
This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.
Alternate Names for Porcine IL-8/CXCL8 DuoSet ELISA, 15 Plate
Background
Interleukin-8 (IL-8), also known as CXCL8, is a chemokine that is upregulated at sites of inflammation where it promotes neutrophil infiltration and activation. IL-8 can form homodimers and heterodimers with CXCL4/PF4. Its bioactivity is regulated by proteolytic truncations, citrullination, and the decoy receptor DARC. IL-8 signals through CXCR1/IL-8 RA, which is also used by CXCL6, and through CXCR2/IL-8 RB, which is used by multiple CXC chemokines. IL-8 also binds to Serpin A1/alpha-1 Antitrypsin which prevents IL-8 interaction with CXCR1.
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Product General Protocols
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FAQs for CXCL8/IL-8 (DY535) (0)