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Peptide YY Antibody (2581A) [Unconjugated]

 
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Simple Western lane view shows lysates of human colon tissue and human small intestine tissue, loaded at 0.2 mg/mL. A specific band was detected for Peptide YY at approximately 3 kDa (as indicated) using 20 µg/mL of Rabbit Anti-Human Peptide YY Monoclonal Antibody (Catalog # MAB94563) . This experiment was conducted under reducing conditions and using the 2-40. kDa separation system.
Simple Western lane view shows lysates of human colon tissue and human small intestine tissue, loaded at 0.2 mg/mL. A specific band was detected for Peptide YY at approximately 3 kDa (as indicated) using 20 ...read more

Product Details

Summary
Reactivity HuSpecies Glossary
Applications Simple Western
Clone
2581A
Clonality
Monoclonal
Host
Rabbit
Conjugate
Unconjugated

Order Details

View Available Formulations
Catalog# & Formulation Size Price
Carrier Free
MAB94563-SP
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Peptide YY Antibody (2581A) [Unconjugated] Summary

Additional Information
Recombinant Monoclonal Antibody.
Immunogen
Human Peptide YY synthetic peptide
Accession # P10082
Specificity
Detects Peptide YY in direct ELISAs.
Source
N/A
Isotype
IgG
Clonality
Monoclonal
Host
Rabbit
Purity Statement
Protein A or G purified from hybridoma culture supernatant
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.
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Applications/Dilutions

Dilutions
  • Simple Western 20 ug/mL

Packaging, Storage & Formulations

Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.
Buffer
Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.
Reconstitution Instructions
Reconstitute at 0.5 mg/mL in sterile PBS.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for Peptide YY Antibody (2581A) [Unconjugated]

  • Peptide tyrosine tyrosine
  • Peptide YY
  • Peptide-YY
  • PYY
  • PYY1
  • PYY-I

Background

Peptide YY (PYY), a secretory peptide, is expressed by L cells (enteroendocrine cells) in the small and large intestine, Islet of Langerhans cells, testis, and in some central and peripheral neurons. Because PYY is released from L cells after feeding, it is thought to produce a satiety signal. While the regulation of appetite by PYY and GLP-1 have been studied extensively, recent evidence supports a role for PYY in Islet of Langerhans beta cell survival. PYY secretion is also modulated by gut microbiota, and levels of colonic PYY have reduced in rats with DSS-induced colitis, and in humans with inflammatory bowel disease (IBD), while circulating PYY increased in IBD.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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