PEG10 Antibody (981902) [DyLight 488]

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications ELISA, CyTOF-ready, Flow
Clone
981902
Clonality
Monoclonal
Host
Mouse
Conjugate
DyLight 488

Order Details

PEG10 Antibody (981902) [DyLight 488] Summary

Immunogen
Synthetic peptide containing human PEG10
Accession # Q86TG7
Specificity
Detects human PEG10 in direct ELISAs.
Isotype
IgG2a
Clonality
Monoclonal
Host
Mouse
Purity
Protein A or G purified from hybridoma culture supernatant
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • CyTOF-ready
  • ELISA
  • Intracellular Staining by Flow Cytometry
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Protein A or G purified from hybridoma culture supernatant

Notes

DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

Alternate Names for PEG10 Antibody (981902) [DyLight 488]

  • EDR
  • embryonal carcinoma differentiation regulated
  • Embryonal carcinoma differentiation-regulated protein
  • HB-1
  • KIAA1051EDR
  • Mammalian retrotransposon-derived protein 2
  • Mar2
  • Mart2
  • MEF3 Like 1
  • MEF3L
  • MEF3L1
  • Myelin expression factor 3-like protein 1
  • paternally expressed 10
  • Paternally expressed gene 10 protein
  • PEG10
  • retrotransposon gag domain containing 3
  • Retrotransposon gag domain-containing protein 3
  • Retrotransposon-derived gag-like polyprotein
  • retrotransposon-derived protein PEG10
  • RGAG3
  • RGAG3MEF3-like protein 1
  • RTL2
  • SIRH1
  • Ty3/Gypsy-like protein

Background

paternally expressed 10. This gene includes two overlapping reading frames of the same transcript encoding distinct isoforms. The shorter isoform has a CCHC-type zinc finger motif containing a sequence characteristic of gag proteins of most retroviruses and some retrotransposons, and it functions in part by interacting with members of the TGF-beta receptor family. The longer isoform has the active-site DSG consensus sequence of the protease domain of pol proteins. The longer isoform is the result of -1 translational frame shifting that is also seen in some retroviruses. Expression of these two isoforms only comes from the paternal allele due to imprinting. Increased gene expression (as observed by an increase in mRNA levels) is associated with hepatocellular carcinomas.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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