PEG10 Antibody (1B1C4) - BSA Free

paternally expressed 10. This gene includes two overlapping reading frames of the same transcript encoding distinct isoforms. The shorter isoform has a CCHC-type zinc finger motif containing a sequence characteristic of gag proteins of most retroviruses and some retrotransposons, and it functions in part by interacting with members of the TGF-beta receptor family. The longer isoform has the active-site DSG consensus sequence of the protease domain of pol proteins. The longer isoform is the result of -1 translational frame shifting that is also seen in some retroviruses. Expression of these two isoforms only comes from the paternal allele due to imprinting. Increased gene expression (as observed by an increase in mRNA levels) is associated with hepatocellular carcinomas.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

We have publications tested in 1 confirmed species: Human.

We have publications tested in 2 applications: IF/IHC, WB.

Showing Publications 1 - 3 of 3.

Publications using NBP1-28875	Applications	Species
Kim S, Thaper D et al. PEG10 is associated with treatment-induced neuroendocrine prostate cancer. J Mol Endocrinol 2019-01-07 [PMID: 31013476] (WB, Human)	WB	Human
Rotinen M, You S, Yang J et al. ONECUT2 Is a Targetable Master Regulator of Lethal Prostate Cancer That Suppresses the Androgen Axis SSRN 2018-12-24 [PMID: 30478421] (IF/IHC, Human)	IF/IHC	Human
Peng YP, Zhu Y, Yin LD et al. PEG10 overexpression induced by E2F-1 promotes cell proliferation, migration, and invasion in pancreatic cancer. J. Exp. Clin. Cancer Res. 2017-02-13 [PMID: 28193232] (IF/IHC, Human)	IF/IHC	Human

Array NBP1-28875

• PEG10 Antibodies
• PEG10 Lysate
• PEG10 Proteins