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PDE10A Antibody (OTI1C9) [Allophycocyanin]

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Product Details

Summary
Reactivity Hu, Mu, RtSpecies Glossary
Applications WB, IHC
Clone
OTI1C9
Clonality
Monoclonal
Host
Mouse
Conjugate
Allophycocyanin

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PDE10A Antibody (OTI1C9) [Allophycocyanin] Summary

Immunogen
Full-length protein expressed in 293T cell transfected with human PDE10A expression vector
Isotype
IgG2b
Clonality
Monoclonal
Host
Mouse
Gene
PDE10A
Purity
Immunogen affinity purified
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Applications/Dilutions

Dilutions
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin
  • Western Blot
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Reactivity Notes

Please note that this antibody is reactive to Mouse and derived from the same host, Mouse. Mouse-On-Mouse blocking reagent may be needed for IHC and ICC experiments to reduce high background signal. You can find these reagents under catalog numbers PK-2200-NB and MP-2400-NB. Please contact Technical Support if you have any questions.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
PBS
Preservative
0.05% Sodium Azide
Purity
Immunogen affinity purified

Alternate Names for PDE10A Antibody (OTI1C9) [Allophycocyanin]

  • cAMP and cAMP-inhibited cGMP 3'-5'-cyclic phosphodiesterase 10A
  • dJ416F21.1 (phosphodiesterase 10A)
  • EC 3.1.4
  • EC 3.1.4.17
  • EC 3.1.4.35
  • FLJ11894
  • FLJ25677
  • HSPDE10A
  • PDE10A
  • phosphodiesterase 10A
  • phosphodiesterase 10A1 (PDE10A1)

Background

One of the many phosphodiesterases that compartmentalize and hydrolyze cAMP and cGMP into AMP and GMP is PDE10. Only one member of the cAMP and cGMP-specific PDE10 family has been cloned and characterized. The PDE10A gene is expressed in at least two variant forms (PDE10A1, PDE10A2) generated by RNA splicing and/or the use of alternate initiation sites. PDE10A is widely expressed in the putamen and caudate nucleus in the brain, thyroid and testis. The expression of PDE10A is also abundant in Heart.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol PDE10A