PCBD2 Antibody [mFluor Violet 610 SE]

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications IHC
Clonality
Polyclonal
Host
Rabbit
Conjugate
mFluor Violet 610 SE

Order Details

PCBD2 Antibody [mFluor Violet 610 SE] Summary

Immunogen
Produced in rabbits immunized with E. coli-derived Human PCBD2 fragment.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
PCBD2
Purity
Antigen and protein A Affinity-purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Immunohistochemistry-Paraffin
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Antigen and protein A Affinity-purified

Notes

mFluor(TM) is a trademark of AAT Bioquest, Inc. This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.

Alternate Names for PCBD2 Antibody [mFluor Violet 610 SE]

  • 4-alpha-hydroxy-tetrahydropterin dehydratase 2
  • DCOH2DCOHMPHS2,6-pyruvoyl-tetrahydropterin synthase/dimerization cofactor of hepatocytenuclear factor 1 alpha (TCF1) 2
  • DcoH-like protein DCoHm
  • dimerization cofactor of hepatocyte nuclear factor 1 (HNF1) from muscle
  • dimerization cofactor of hepatocyte nuclear factor 1 alpha (TCF1)
  • Dimerization cofactor of hepatocyte nuclear factor 1 from muscle
  • EC 4.2.1.96
  • HNF-1-alpha dimerization cofactor
  • PHS 2
  • pterin-4 alpha-carbinolamine dehydratase 2
  • pterin-4 alpha-carbinolamine dehydratase/dimerization cofactor of hepatocytenuclear factor 1 alpha (TCF1) 2
  • pterin-4-alpha-carbinolamine dehydratase 2

Background

PCBD2, also known as Pterin-4-alpha-carbinolamine dehydratase 2, is a 130 amino acid protein that is 14 kDa, involved in tetrahydrobiopterin biosynthesis preventing the formation of 7-pterins and accelerating the formation of quinonoid-BH2, also being known to regulate the dimerization of homeodomain protein HNF-1-alpha and enhances its transcriptional activity. The protein is being studied for its involvement in hyperphenylalaninemia. The PCBD2 has also been shown to have interactions with DYRK1B, AATF, ASCC2, C1D, and CHAF1A in pathways such as phenylalanine degradation I (aerobic) pathway.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol PCBD2