Pax3 Antibody

This protein is a member of the paired box (PAX) family of transcription factors. Members of the PAX family typically contain a paired box domain and a paired-type homeodomain. These proteins play critical roles during fetal development. Mutations in paired box gene 3 are associated with Waardenburg syndrome, craniofacial-deafness-hand syndrome, and alveolar rhabdomyosarcoma. The translocation t(2;13)(q35;q14), which represents a fusion between PAX3 and the forkhead gene, is a frequent finding in alveolar rhabdomyosarcoma. Alternative splicing results in transcripts encoding isoforms with different C-termini.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

We have publications tested in 1 confirmed species: Human.

We have publications tested in 2 applications: IP, WB.

Showing Publications 1 - 3 of 3.

Publications using NB100-1420	Applications	Species
Suzuki R, Murata MM, Manguso N et al. The fragility of a structurally diverse duplication block triggers recurrent genomic amplification Nucleic acids research 2020-12-08 [PMID: 33290559] (WB, Human)	WB	Human
Hsieh MJ, Yao YL, Lai IL et al. Transcriptional repression activity of PAX3 is modulated by competition between corepressor KAP1 and heterochromatin protein 1. Biochem Biophys Res Commun. 2006-10-20 [PMID: 16945326] (IP) Details: Immunopreciptation, Figure 3 B.	IP
Tsukamoto K, Nakamura Y, Niikawa N. Isolation of two isoforms of the PAX3 gene transcripts and their tissue-specific alternative expression in human adult tissues. Hum Genet 1994-03-01 [PMID: 7545913]

Array NB100-1420

• Pax3 Antibodies
• Pax3 Lysate
• Pax3 Proteins