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OX40/TNFRSF4 Antibody (OX-86) [DyLight 650]

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Product Details

Summary
Reactivity MuSpecies Glossary
Applications Flow, IHC
Clone
OX-86
Clonality
Monoclonal
Host
Rat
Conjugate
DyLight 650

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price
Alexa Fluor 350
NB100-64847AF350
Alexa Fluor 405
NB100-64847AF405
Alexa Fluor 488
NB100-64847AF488
Alexa Fluor 532
NB100-64847AF532
Alexa Fluor 594
NB100-64847AF594
Alexa Fluor 647
NB100-64847AF647
Alexa Fluor 700
NB100-64847AF700
Alexa Fluor 750
NB100-64847AF750
Allophycocyanin
NB100-64847APC
Biotin
NB100-64847B
DyLight 350
NB100-64847UV
DyLight 405
NB100-64847V
DyLight 488
NB100-64847G
DyLight 550
NB100-64847R
DyLight 594
NB100-64847DL594
DyLight 680
NB100-64847FR
DyLight 755
NB100-64847IR
FITC
NB100-64847F
HRP
NB100-64847H
Janelia Fluor 549
NB100-64847JF549
Janelia Fluor 646
NB100-64847JF646
PE
NB100-64847PE
PerCP
NB100-64847PCP
Unconjugated
NB100-64847
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OX40/TNFRSF4 Antibody (OX-86) [DyLight 650] Summary

Description
This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.
Immunogen
CHO cells transfected with murine OX40
Localization
Cell Membrane. Type I membrane protein.
Specificity
NB100-64847 recognises murine OX40 (CD134), a cell surface antigen expressed only by activated T lymphocytes.
Isotype
IgG1
Clonality
Monoclonal
Host
Rat
Gene
TNFRSF4
Purity
Protein G purified
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Applications/Dilutions

Dilutions
  • Flow Cytometry
  • Immunohistochemistry
  • Immunohistochemistry-Frozen
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Protein G purified

Notes



DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

Alternate Names for OX40/TNFRSF4 Antibody (OX-86) [DyLight 650]

  • ACT-135
  • ACT35 antigen
  • ACT35ATC35 antigen
  • CD134 antigen
  • CD134
  • Ly-70
  • OX40 cell surface antigen
  • OX40 homologue
  • OX40
  • OX40L receptor
  • OX40lymphoid activation antigene ACT35
  • TAX transcriptionally-activated glycoprotein 1 receptor
  • tax-transcriptionally activated glycoprotein 1 receptor
  • TNFRSF4
  • tumor necrosis factor receptor superfamily member 4
  • tumor necrosis factor receptor superfamily, member 4
  • Txgp1
  • TXGP1L
  • TXGP1LOX40 antigen

Background

The OX40 receptor is also known as CD134, ACT35, and tumor necrosis factor receptor superfamily member 4. This receptor is expressed on activated CD4+ and CD8+ T cells and B cells. The OX40 receptor binds to the OX40 ligand to provide a co-stimulatory signal that is independent of CD28. Blockade of OX40-OX40 ligand interactions has been shown to ameliorate experimental EAE and inflammatory bowel disease, imply that these interactions are important in the pathogenesis of some autoimmune diseases.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol TNFRSF4
Entrez