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Osteoactivin/GPNMB Antibody (105) [Janelia Fluor® 549]

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications ELISA
Clone
105
Clonality
Monoclonal
Host
Rabbit
Conjugate
Janelia Fluor 549

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price
Alexa Fluor 350
NBP2-89886AF350
Alexa Fluor 405
NBP2-89886AF405
Alexa Fluor 488
NBP2-89886AF488
Alexa Fluor 532
NBP2-89886AF532
Alexa Fluor 594
NBP2-89886AF594
Alexa Fluor 647
NBP2-89886AF647
Alexa Fluor 700
NBP2-89886AF700
Alexa Fluor 750
NBP2-89886AF750
Allophycocyanin
NBP2-89886APC
Biotin
NBP2-89886B
CoraFluor 1
NBP2-89886CL1
DyLight 350
NBP2-89886UV
DyLight 405
NBP2-89886V
DyLight 488
NBP2-89886G
DyLight 550
NBP2-89886R
DyLight 594
NBP2-89886DL594
DyLight 650
NBP2-89886C
DyLight 680
NBP2-89886FR
DyLight 755
NBP2-89886IR
FITC
NBP2-89886F
HRP
NBP2-89886H
Janelia Fluor 525
NBP2-89886JF525
Janelia Fluor 646
NBP2-89886JF646
Janelia Fluor 669
NBP2-89886JF669
PE
NBP2-89886PE
PerCP
NBP2-89886PCP
Unconjugated
NBP2-89886-100ul
mFluor Violet 450 SE
NBP2-89886MFV450
mFluor Violet 500 SE
NBP2-89886MFV500
mFluor Violet 610 SE
NBP2-89886MFV610
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Osteoactivin/GPNMB Antibody (105) [Janelia Fluor® 549] Summary

Additional Information
Recombinant Monoclonal Antibody
Immunogen
This antibody was obtained from a rabbit immunized with purified, recombinant Human Osteoactivin/GPNMB (Uniprot#: Q14956-2; Met1-Pro474).
Isotype
IgG
Clonality
Monoclonal
Host
Rabbit
Gene
GPNMB
Purity
Protein A purified
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Applications/Dilutions

Dilutions
  • ELISA
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Protein A purified

Notes

Sold under license from the Howard Hughes Medical Institute, Janelia Research Campus.

Alternate Names for Osteoactivin/GPNMB Antibody (105) [Janelia Fluor® 549]

  • DC-HIL
  • glycoprotein (transmembrane) nmb
  • glycoprotein NMB
  • GPNMB
  • HGFIN
  • HGFINglycoprotein nmb-like protein
  • NMBosteoactivin
  • Osteoactivin
  • Transmembrane glycoprotein HGFIN
  • transmembrane glycoprotein NMB

Background

The GPNMB gene codes for a type I transmembrane glycoprotein NBM. The GPNMB gene is present in lowly, but not highly, metastic human melanoma cell lines, therefore, it demonstrates involvement in development, proliferation, and differentiation of tissues. Isoform 1 is 572 amino acids long at a mass of nearly 64 kDA and isoform 2 exists at 560 amino acids long at approximately 62 kDA. This gene has been known to interact with various genes such as SMAD4, PLA2G4A, and ITSN2. GPNMB has been researched in its role in retinitis, lung cancer, melanoma, glioblastoma, glaucoma, and breast cancer.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol GPNMB