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OAS2 Antibody (HLS56/3) [Unconjugated]

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OAS2 was detected in immersion fixed U266 human myeloma cell line using Mouse Anti-Human OAS2 Monoclonal Antibody (Catalog # MAB1925) at 3 µg/mL for 3 hours at room temperature. Cells were stained using the NorthernLights™ 557-conjugated Anti-Mouse IgG Secondary Antibody (red; NL007) and counterstained with DAPI (blue). Specific staining was localized to cytoplasm. Staining was performed using our protocol for Fluorescent ICC Staining of Non-adherent Cells.
OAS2 was detected in immersion fixed U266 human myeloma cell line using Mouse Anti-Human OAS2 Monoclonal Antibody (Catalog # MAB1925) at 3 µg/mL for 3 hours at room temperature. Cells were stained using the ...read more

Product Details

Summary
Reactivity HuSpecies Glossary
Applications IP, ICC/IF
Clone
HLS56/3
Clonality
Monoclonal
Host
Mouse
Conjugate
Unconjugated

Order Details

View Available Formulations
Catalog# & Formulation Size Price
Carrier Free
MAB1925-SP
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OAS2 Antibody (HLS56/3) [Unconjugated] Summary

Immunogen
2’,5’-Oligoadenylate Synthetase-2
Specificity
Detects human OAS2.
Source
N/A
Isotype
IgG2a
Clonality
Monoclonal
Host
Mouse
Gene
OAS2
Purity Statement
Protein A or G purified from hybridoma culture supernatant
Innovator's Reward
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Applications/Dilutions

Dilutions
  • Immunocytochemistry 3-25 ug/mL
  • Immunoprecipitation
Publications
Read Publications using
MAB1925 in the following applications:

Packaging, Storage & Formulations

Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.
Buffer
Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.
Preservative
No Preservative
Reconstitution Instructions
Reconstitute at 0.5 mg/mL in sterile PBS.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for OAS2 Antibody (HLS56/3) [Unconjugated]

  • (2-5')oligo(A) synthase 2
  • (2'-5')oligo(A) synthetase 2
  • (2-5')oligo(A) synthetase 2
  • 2'5' oligoadenylate synthetase 2
  • 2-5A synthase 2
  • 2-5A synthetase 2
  • 2'-5'-oligoadenylate synthase 2
  • 2'-5'-oligoadenylate synthetase 2 (69-71 kD)
  • 2'-5'-oligoadenylate synthetase 2, 69/71kDa
  • EC 2.7.7
  • EC 2.7.7.-
  • MGC78578
  • OAS2
  • p69 OAS / p71 OAS
  • p69OAS / p71OAS

Background

OAS2, also known as OAS (69 kDa), is one of three related proteins (along with OAS1 and OAS3) that catalyze the conversion of ATP into 2’,5’-linked adenosine oligomers with the general formula pppA(2’,5’A)n where n > 1 (2, 3) These proteins are induced by interferons, activated by double-stranded RNA, and are implicated in anti-viral immunity (1, 4, 5).
  1. Hovanessian, A.G. et al. (1987) EMBO J. 6:1273.
  2. Hovanessian, A.G. et al. (1977) Nature 268:537.
  3. Kerr, I.M. and R.E. Brown (1978) Proc. Natl. Acad. Sci. USA 75:256.
  4. Hovanessian, A.G. et al. (1988) J. Biol. Chem. 263:4959.
  5. Marie, I. et al. (1990) J. Interferon Res. 10:571.
  6. Marie, I. et al. (1990) J. Biol. Chem. 265:18601.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for OAS2 Antibody (MAB1925)(2)

We have publications tested in 1 confirmed species: Human.

We have publications tested in 2 applications: Immunoprecipitation, Western Blot.


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Secondary Antibodies

 

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Bioinformatics

Gene Symbol OAS2