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Neuromedin BR/NMBR Antibody (466505) [PerCP]

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications Flow, CyTOF-ready, Flow
Clone
466505
Clonality
Monoclonal
Host
Mouse
Conjugate
PerCP

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Neuromedin BR/NMBR Antibody (466505) [PerCP] Summary

Immunogen
NS0 mouse myeloma cell line transfected with human NMBR
Met1-Met390
Accession # AAB27330
Specificity
Detects human Neuromedin B R/NMBR. Stains human Neuromedin B R/NMBR transfectants but not irrelevant transfectants.
Isotype
IgG2a
Clonality
Monoclonal
Host
Mouse
Gene
NMBR
Purity
Protein A or G purified from hybridoma culture supernatant
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • CyTOF-ready
  • Flow Cytometry
  • Intracellular Staining by Flow Cytometry
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
PBS
Preservative
0.05% Sodium Azide
Purity
Protein A or G purified from hybridoma culture supernatant

Alternate Names for Neuromedin BR/NMBR Antibody (466505) [PerCP]

  • Neuromedin B R
  • neuromedin B receptor
  • Neuromedin BR
  • neuromedin-B receptor
  • Neuromedin-B-preferring bombesin receptor
  • NMBR
  • NMB-R

Background

The neuromedin B receptor, a Bombesin Receptor, activates phospholipase and protein kinase C and enhances calcium mobilization. It binds neuromedin B, a potent mitogen and growth factor for normal and neoplastic lung and for gastrointestinal epithelial tissues. Neuromedin B receptor expression has been reported in brain, particularly the olfactory bulb and thalamus, and in colon, liver, placenta, testis, spinal cord, and gastrointestinal tract. In addition, it has been shown to be present in cancer of the lung, ovary, and prostate. ESTs have been isolated from B-cell/lung/testis and brain libraries.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Secondary Antibodies

 

Isotype Controls

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Bioinformatics

Gene Symbol NMBR