Detects human NRG1 Isoform GGF2 in direct ELISAs and Western blots. In direct ELISAs, less than 1% cross‑reactivity with recombinant human (rh) NRG‑1 alpha EGF domain, rhNRG1-beta 1 extracellular domain, rhNRG1-beta 1 EGF domain, rhSMDF, and recombinant mouse NRG3 is observed.
Source
N/A
Isotype
IgG
Clonality
Polyclonal
Host
Goat
Gene
NRG1
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Store the unopened product at -20 to -70 °C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date.
Buffer
Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. See Certificate of Analysis for details. *Small pack size (-SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.
Preservative
No Preservative
Concentration
LYOPH
Reconstitution Instructions
Reconstitute at 0.2 mg/mL in sterile PBS. For liquid material, refer to CoA for concentration.
Notes
This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.
Alternate Names for Neuregulin-1 Isoform GGF2 Antibody
GGF2
ARIA
GGF
GGF2
HGL
HRG
HRG1
HRGA
MST131
MSTP131
NDF
Neuregulin1 Isoform GGF2
Neuregulin-1 Isoform GGF2
NRG1-IT2
SMDF
Background
By alternative splicing, the Neuregulin 1 gene ecodes at least 10
secreted or membrane-bound proteins, all of which contain an EGF-like
domain. Neuregulin 1 isoforms bind and signal via the ErbB family of
receptor tyrosine kinases. Isoform GGF2 contains a unique kringle-like
domain, plus Ig and EGF-like domains that are also present in multiple
Neuregulin 1 isoforms.
Limitations
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
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