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MTA2 Antibody [mFluor Violet 500 SE]

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Product Details

Summary
Reactivity Hu, Pm, Mu, RtSpecies Glossary
Applications WB, ICC/IF, IHC
Clonality
Polyclonal
Host
Rabbit
Conjugate
mFluor Violet 500 SE

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price
Alexa Fluor 350
NB100-56483AF350
Alexa Fluor 405
NB100-56483AF405
Alexa Fluor 488
NB100-56483AF488
Alexa Fluor 532
NB100-56483AF532
Alexa Fluor 594
NB100-56483AF594
Alexa Fluor 647
NB100-56483AF647
Alexa Fluor 700
NB100-56483AF700
Alexa Fluor 750
NB100-56483AF750
Allophycocyanin
NB100-56483APC
Biotin
NB100-56483B
CoraFluor 1
NB100-56483CL1
DyLight 350
NB100-56483UV
DyLight 405
NB100-56483V
DyLight 488
NB100-56483G
DyLight 550
NB100-56483R
DyLight 594
NB100-56483DL594
DyLight 650
NB100-56483C
DyLight 680
NB100-56483FR
DyLight 755
NB100-56483IR
FITC
NB100-56483F
HRP
NB100-56483H
Janelia Fluor 525
NB100-56483JF525
Janelia Fluor 549
NB100-56483JF549
Janelia Fluor 646
NB100-56483JF646
Janelia Fluor 669
NB100-56483JF669
PE
NB100-56483PE
PerCP
NB100-56483PCP
Unconjugated
NB100-56483
mFluor Violet 450 SE
NB100-56483MFV450
mFluor Violet 610 SE
NB100-56483MFV610
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MTA2 Antibody [mFluor Violet 500 SE] Summary

Immunogen
A portion of amino acids 650-700 of human MTA2 was used as the immunogen (NP_004730).
Predicted Species
Mouse (94%), Rat (94%). Backed by our 100% Guarantee.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
MTA2
Purity
Immunogen affinity purified
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Applications/Dilutions

Dilutions
  • Immunocytochemistry/ Immunofluorescence
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin
  • Western Blot
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Reactivity Notes

Predicted cross-reactivity based on sequence identity: Dog (88%), Bovine (88%) and Xenopus (76%).

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Immunogen affinity purified

Notes

mFluor(TM) is a trademark of AAT Bioquest, Inc. This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.

Alternate Names for MTA2 Antibody [mFluor Violet 500 SE]

  • DKFZp686F2281
  • metastasis associated 1 family, member 2
  • metastasis -associated gene 1-like 1
  • metastasis associated gene family, member 2
  • Metastasis-associated 1-like 1
  • metastasis-associated protein 2
  • metastasis-associated protein MTA2
  • MTA1-L1 protein
  • MTA1L1MTA1-L1
  • p53 target protein in deacetylase complex
  • PID

Background

Official Gene Symbol: MTA2 Gen Bank Accession Number: NP_004730 Gene ID: 9219 (Human) Gene Map Locus: 11q12-q13.1 (human) MTA2, a homologue of human MTA1 and MTA3, is a member of highly conserved MTA gene family. It is a component of NuRD, an ATP-dependent nucleosome remodeling and histone deacetylase complex. MTA2 is a nuclear protein that interacts with HDAC1 and HDAC2 and has a functional role in chromatin remodeling and deacetylase activity. MTA2 specifically interacts with p53 and represses p53-dependant transcriptional activation, thereby regulating p53-mediated cell growth arrest and apoptosis. It also inhibits the transcriptional activity of Estrogen receptor-alpha. Northern Blot analysis detected a ubiquitous expression of MTA2.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Secondary Antibodies

 

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Bioinformatics

Gene Symbol MTA2