Mouse RBP4 Quantikine ELISA Kit

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Retinol-binding protein 4 (RBP4) is a Lipocalin superfamily molecule that transports vitamin A (retinol) and retinaldehyde in the serum. Retinaldehyde is the critical chromophore in the rhodopsin photoreceptor, while both it and retinoic acid regulate a multitude of cellular differentiation and proliferation effects through the intracellular receptors RAR and RXR. RBP4 is secreted primarily by hepatocytes and adipocytes into the blood where the RBP4-retinol complex interacts with transthyretin (TTR). Formation of the complex with TTR increases the serum half-life of RBP4 by preventing RBP4 filtration through the kidney. The C-terminally processed forms of RBP4, which do not bind TTR, are normally excreted into the urine but accumulate in the serum during renal failure. RBP4 promotes hyperglycemia, and its upregulation in visceral and liver adipocytes leads to elevated serum levels.

We have publications tested in 1 confirmed species: Mouse.

Showing Publications 1 - 4 of 4.

Publications using MRBP40	Applications	Species
J Liu, C Nie, L Xue, Y Yan, S Liu, J Sun, M Fan, H Qian, H Ying, L Wang, Y Li Growth hormone receptor disrupts glucose homeostasis via promoting and stabilizing retinol binding protein 4 Theranostics, 2021-07-13;11(17):8283-8300. 2021-07-13 [PMID: 34373742] (Mouse)		Mouse
K Annu, C Cline, K Yasuda, S Ganguly, A Pesch, B Cooper, L Janke, M Payton, K Mukherjee, SL Surman, JL Hurwitz, EG Schuetz Role of Vitamins A and D in BCR-ABL Arf-/- Acute Lymphoblastic Leukemia Sci Rep, 2020-02-11;10(1):2359. 2020-02-11 [PMID: 32047189] (Mouse)		Mouse
M Du, E Phelps, MJ Balangue, A Dockins, G Moiseyev, Y Shin, S Kane, L Otalora, JX Ma, R Farjo, KM Farjo Transgenic Mice Over-Expressing RBP4 Have RBP4-Dependent and Light-Independent Retinal Degeneration Invest. Ophthalmol. Vis. Sci., 2017-08-01;58(10):4095-4103. 2017-08-01 [PMID: 28813718] (Mouse)		Mouse
M Du, A Martin, F Hays, J Johnson, RA Farjo, KM Farjo Serum retinol-binding protein-induced endothelial inflammation is mediated through the activation of toll-like receptor 4 Mol. Vis., 2017-03-31;23(0):185-197. 2017-03-31 [PMID: 28400700] (Mouse)		Mouse

Array MRBP40

• RBP4/Retinol-Binding Protein 4 Antibodies
• RBP4/Retinol-Binding Protein 4 Antibody Pair
• RBP4/Retinol-Binding Protein 4 ELISA Kits
• RBP4/Retinol-Binding Protein 4 Lysate
• RBP4/Retinol-Binding Protein 4 Proteins
• RBP4/Retinol-Binding Protein 4 ELISAs
• RBP4/Retinol-Binding Protein 4 Proteins and Enzymes