Mouse IL-23 Quantikine ELISA Kit

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

IL-23 (Interleukin-23) is a disulfide-linked cytokine composed of a p19 subunit that is unique to IL-23 and a p40 subunit that is shared with IL-12. It is produced by activated macrophages, microglia, and monocyte-derived dendritic cells in response to pathogens. IL-23 induces the earliest recruitment of neutrophils to the site of infection and promotes the development and maintenance of Th17 cells. It also enhances the development of Th17 mediated autoimmunity and tumor progression. IL-23 signals through a receptor complex consisting of IL-12 R beta 1 and IL-23 R. This complex is expressed in mouse Th1 and Th2 cells, bone marrow dendritic cells, activated macrophages and CD4+ CD45Rb(low) memory T cells.

We have publications tested in 1 confirmed species: Mouse.

Showing Publications 1 - 10 of 26. Show All 26 Publications. Collapse Publications.

Publications using M2300	Applications	Species
Kurosu, T;Okuzaki, D;Sakai, Y;Kadi, MA;Phanthanawiboon, S;Ami, Y;Shimojima, M;Yoshikawa, T;Fukushi, S;Nagata, N;Suzuki, T;Kamimura, D;Murakami, M;Ebihara, H;Saijo, M; Dengue virus infection induces selective expansion of V?4 and V?6TCR ?? T cells in the small intestine and a cytokine storm driving vascular leakage in mice PLoS neglected tropical diseases 2023-11-01 [PMID: 37939119] (Mouse)		Mouse
J Wang, S Wu, Z Li, L Liu, Y Pang, J Wei Selective NF-kappaB inducing kinase inhibitor attenuates the onset of chronic periodontitis The international journal of biochemistry & cell biology, 2021-08-05;0(0):106052. 2021-08-05 [PMID: 34364989] (Mouse)		Mouse
L Lu, Y Wang, L Zhou, Y Li, X Zhang, X Hu, S Shi, W He V&gamma4 T cell-derived IL-17A is essential for amplification of inflammatory cascades in ischemic brain tissue after stroke International immunopharmacology, 2021-05-24;96(0):107678. 2021-05-24 [PMID: 34162129] (Mouse)		Mouse
LT Wang, MH Lin, KY Liu, SS Chiou, SN Wang, CY Chai, LW Tseng, HC Chiou, HC Wang, KK Yokoyama, SH Hsu, SK Huang WLS/wntless is essential in controlling dendritic cell homeostasis via a WNT signaling-independent mechanism Autophagy, 2021-04-14;0(0):1-16. 2021-04-14 [PMID: 33853474] (Mouse)		Mouse
B Zhang, RC Lai, WK Sim, ABH Choo, EB Lane, SK Lim Topical Application of Mesenchymal Stem Cell Exosomes Alleviates the Imiquimod Induced Psoriasis-Like Inflammation International Journal of Molecular Sciences, 2021-01-13;22(2):. 2021-01-13 [PMID: 33450859] (Mouse)		Mouse
C Wei, JY Wang, F Xiong, BH Wu, MH Luo, ZC Yu, TT Liu, DF Li, Q Tang, YX Li, DG Zhang, ZL Xu, HT Jin, LS Wang, J Yao Curcumin ameliorates DSS?induced colitis in mice by regulating the Treg/Th17 signaling pathway Mol Med Rep, 2020-11-12;23(1):. 2020-11-12 [PMID: 33179078] (Mouse)		Mouse
M Nakao, T Miyagaki, M Sugaya, S Sato Exacerbated Imiquimod-Induced Psoriasis-Like Skin Inflammation in IRF5-Deficient Mice Int J Mol Sci, 2020-05-23;21(10):. 2020-05-23 [PMID: 32456211] (Mouse)		Mouse
M Chen, J Peng, Q Xie, N Xiao, X Su, H Mei, Y Lu, J Zhou, Y Dai, S Wang, C Li, G Lin, L Cheng Mesenchymal Stem Cells Alleviate Moderate-to-Severe Psoriasis by Reducing the Production of Type I Interferon (IFN-I) by Plasmacytoid Dendritic Cells (pDCs) Stem Cells Int, 2019-11-07;2019(0):6961052. 2019-11-07 [PMID: 31827531] (Mouse)		Mouse
K Kobayashi, Y Honme, T Sashihara Lactobacillus delbrueckii subsp. bulgaricus 2038 and Streptococcus thermophilus 1131 Induce the Expression of the REG3 Family in the Small Intestine of Mice via the Stimulation of Dendritic Cells and Type 3 Innate Lymphoid Cells Nutrients, 2019-12-07;11(12):. 2019-12-07 [PMID: 31817820] (Mouse)		Mouse
S Doppalapud, A Jain, W Khan, AJ Domb Fenoldopam mesylate for treating psoriasis: A new indication for an old drug Int J Pharm, 2019-11-09;0(0):118726. 2019-11-09 [PMID: 31715365] (Mouse)		Mouse
N Ju, M Shimamura, H Hayashi, Y Ikeda, S Yoshida, A Nakamura, R Morishita, H Rakugi, H Nakagami Preventative effects of the partial RANKL peptide MHP1-AcN in a mouse model of imiquimod-induced psoriasis Sci Rep, 2019-10-28;9(1):15434. 2019-10-28 [PMID: 31659208] (Mouse)		Mouse
J Zhang, H Li, Q Wu, Y Chen, Y Deng, Z Yang, L Zhang, B Liu Tumoral NOX4 recruits M2 tumor-associated macrophages via ROS/PI3K signaling-dependent various cytokine production to promote NSCLC growth Redox Biol, 2019-02-06;22(0):101116. 2019-02-06 [PMID: 30769285] (Mouse)		Mouse
YH Kwon, H Wang, E Denou, JE Ghia, L Rossi, ME Fontes, SP Bernier, MS Shajib, S Banskota, SM Collins, MG Surette, WI Khan Modulation of Gut Microbiota Composition by Serotonin Signaling Influences Intestinal Immune Response and Susceptibility to Colitis Cell Mol Gastroenterol Hepatol, 2019-02-01;0(0):. 2019-02-01 [PMID: 30716420] (Mouse)		Mouse
H Zhu, F Lou, Q Yin, Y Gao, Y Sun, J Bai, Z Xu, Z Liu, W Cai, F Ke, L Zhang, H Zhou, H Wang, G Wang, X Chen, H Zhang, Z Wang, F Ginhoux, C Lu, B Su, H Wang RIG-I antiviral signaling drives interleukin-23 production and psoriasis-like skin disease EMBO Mol Med, 2017-05-01;9(5):589-604. 2017-05-01 [PMID: 28377495] (Mouse)		Mouse
Guerra E, Lee C, Specht C, Yadav B, Huang H, Akalin A, Huh J, Mueller C, Levitz S Central Role of IL-23 and IL-17 Producing Eosinophils as Immunomodulatory Effector Cells in Acute Pulmonary Aspergillosis and Allergic Asthma. PLoS Pathog, 2017-01-17;13(1):e1006175. 2017-01-17 [PMID: 28095479] (Mouse)		Mouse
Lees J, Duffy S, Perera C, Moalem-Taylor G Depletion of Foxp3+ regulatory T cells increases severity of mechanical allodynia and significantly alters systemic cytokine levels following peripheral nerve injury. Cytokine, 2014-11-20;71(2):207-14. 2014-11-20 [PMID: 25461400] (Mouse)		Mouse
Qin S, Wen J, Bai X, Chen T, Zheng R, Zhou G, Ma J, Feng J, Zhong B, Li Y Endogenous n-3 polyunsaturated fatty acids protect against imiquimod-induced psoriasis-like inflammation via the IL-17/IL-23 axis. Mol Med Rep, 2014-04-09;9(6):2097-104. 2014-04-09 [PMID: 24718773] (Mouse)		Mouse
Bugl S, Wirths S, Radsak M, Schild H, Stein P, Andre M, Muller M, Malenke E, Wiesner T, Marklin M, Frick J, Handgretinger R, Rammensee H, Kanz L, Kopp H Steady-state neutrophil homeostasis is dependent on TLR4/TRIF signaling. Blood, 2012-12-05;121(5):723-33. 2012-12-05 [PMID: 23223360] (Mouse)		Mouse
Ylostalo J, Bartosh T, Coble K, Prockop D Human mesenchymal stem/stromal cells cultured as spheroids are self-activated to produce prostaglandin E2 that directs stimulated macrophages into an anti-inflammatory phenotype. Stem Cells, 2012-10-01;30(10):2283-96. 2012-10-01 [PMID: 22865689] (Mouse)		Mouse
Elevating body temperature enhances hematopoiesis and neutrophil recovery after total body irradiation in an IL-1-, IL-17-, and G-CSF-dependent manner. Blood, 2012-07-17;120(13):2600-9. 2012-07-17 [PMID: 22806894] (Mouse)		Mouse
A protective role for human IL-10-expressing CD4+ T cells in colitis. J. Immunol., 2012-06-29;189(3):1243-52. 2012-06-29 [PMID: 22753934] (Mouse)		Mouse
DePaolo RW, Abadie V, Tang F Co-adjuvant effects of retinoic acid and IL-15 induce inflammatory immunity to dietary antigens. Nature, 2011-02-09;471(7337):220-4. 2011-02-09 [PMID: 21307853] (Mouse)		Mouse
Wang J, Ma J, Charboneau R Morphine Inhibits Murine Dendritic Cell IL-23 Production by Modulating Toll-like Receptor 2 and Nod2 Signaling. J. Biol. Chem., 2011-01-18;286(12):10225-32. 2011-01-18 [PMID: 21245149] (Mouse)		Mouse
Kudva A, Scheller EV, Robinson KM Influenza A inhibits Th17-mediated host defense against bacterial pneumonia in mice. J. Immunol., 2010-12-22;186(3):1666-74. 2010-12-22 [PMID: 21178015] (Mouse)		Mouse
Ma J, Wang J, Wan J, Charboneau R, Chang Y, Barke RA, Roy S Morphine disrupts interleukin-23 (IL-23)/IL-17-mediated pulmonary mucosal host defense against Streptococcus pneumoniae infection. Infect. Immun., 2009-12-07;78(2):830-7. 2009-12-07 [PMID: 19995896] (Mouse)		Mouse
Meiron M, Zohar Y, Anunu R, Wildbaum G, Karin N CXCL12 (SDF-1alpha) suppresses ongoing experimental autoimmune encephalomyelitis by selecting antigen-specific regulatory T cells. J. Exp. Med., 2008-10-13;205(11):2643-55. 2008-10-13 [PMID: 18852294] (Mouse)		Mouse
Show All 26 Publications. Collapse Publications.

Array M2300

• IL-23A/IL-23 P19 Antibodies
• IL-23A/IL-23 P19 Lysate
• IL-23A/IL-23 P19 Proteins
• IL-23A/IL-23 P19 ELISAs
• IL-23A/IL-23 P19 Proteins and Enzymes