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MMP-2 Antibody (2C1) [DyLight 650]

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Product Details

Summary
Reactivity Hu, Mu, Rt, GpSpecies Glossary
Applications WB, ELISA, Flow, ICC/IF, IHC, IP
Clone
2C1
Clonality
Monoclonal
Host
Mouse
Conjugate
DyLight 650

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price
Alexa Fluor 350
NB200-113AF350
Alexa Fluor 405
NB200-113AF405
Alexa Fluor 488
NB200-113AF488
Alexa Fluor 532
NB200-113AF532
Alexa Fluor 594
NB200-113AF594
Alexa Fluor 647
NB200-113AF647
Alexa Fluor 700
NB200-113AF700
Alexa Fluor 750
NB200-113AF750
Biotin
NB200-113B
DyLight 350
NB200-113UV
DyLight 405
NB200-113V
DyLight 488
NB200-113G
DyLight 550
NB200-113R
DyLight 594
NB200-113DL594
DyLight 680
NB200-113FR
DyLight 755
NB200-113IR
FITC
NB200-113F
HRP
NB200-113H
Janelia Fluor 549
NB200-113JF549
Janelia Fluor 646
NB200-113JF646
Unconjugated
NB200-113
mFluor Violet 450 SE
NB200-113MFV450
mFluor Violet 500 SE
NB200-113MFV500
mFluor Violet 610 SE
NB200-113MFV610
View Available Formulations
Catalog# & Formulation Size Price
Standard Formulation
NB200-113
BSA Free
NB200-113SS
BSA Free
NB200-113
Azide and BSA Free
NBP2-80853
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MMP-2 Antibody (2C1) [DyLight 650] Summary

Immunogen
Activated recombinant human MMP2. [UniProt# P08253]
Specificity
This is specific for pro and active MMP-2.
Isotype
IgG1 Kappa
Clonality
Monoclonal
Host
Mouse
Gene
MMP2
Purity
Protein G purified
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Applications/Dilutions

Dilutions
  • ELISA
  • Flow Cytometry
  • Immunocytochemistry/ Immunofluorescence
  • Immunohistochemistry
  • Immunohistochemistry-Frozen
  • Immunohistochemistry-Paraffin
  • Immunoprecipitation
  • Western Blot
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Protein G purified

Notes



DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

Alternate Names for MMP-2 Antibody (2C1) [DyLight 650]

  • 72 kDa gelatinase
  • CLG4
  • CLG4A72 kDa type IV collagenase
  • collagenase type IV-A
  • EC 3.4.24
  • EC 3.4.24.24
  • Gelatinase A
  • matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IVcollagenase)
  • matrix metalloproteinase 2 (gelatinase A, 72kD gelatinase, 72kD type IVcollagenase)
  • Matrix metalloproteinase-2
  • matrix metalloproteinase-II
  • MMP2
  • MMP-2
  • MMP-II
  • MONA
  • neutrophil gelatinase
  • TBE-1matrix metalloproteinase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IVcollagenase)

Background

Loss of negative growth regulation and high invasive potential are neoplastic traits often associated with abnormal expression of matrix matalloproteinases. MMP-2, a protein involved in the signaling mechanism for cells to begin migration, triggers the movement when it splits laminin-5 and exposes and integrin-binding site on this component of epithelial basement membrane. The changed form of laminin was found in tumors and in tissues being altered. The activated form of MMP2, however, is not found in benign tumors. Thus, detection of the enzyme is a possible early indicator of tumor activity.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

Find general support by application which include: protocols, troubleshooting, illustrated assays, videos and webinars.

Video Protocols

WB Video Protocol
ICC/IF Video Protocol

FAQs for MMP-2 Antibody (NB200-113C) (0)

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Secondary Antibodies

 

Isotype Controls

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Bioinformatics

Gene Symbol MMP2