MMP-13 Antibody (OTI2D8)

The matrix metalloproteinases (MMP) are a family of peptidase enzymes responsible for the degradation of extracellular matrix components, including collagen, gelatin, fibronectin, laminin and proteoglycan. Transcription of MMP genes is differentially activated by phorbol ester, lipopolysaccharide (LPS) or staphylococcal enterotoxin B (SEB). MMP catalysis requires both calcium and zinc. MMP-12 (also designated macrophage metalloelastase) is produced in alveolar macrophages and degrades elastin. MMP-12 may contribute to elastin degradation occurring in granulomatous skin diseases and may also participate in macrophage migration through the epidermal and vascular basement membranes in inflammatory disorders.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

We have publications tested in 2 confirmed species: Mouse, Rat.

We have publications tested in 4 applications: IF/IHC, IHC-P, KD, WB.

Showing Publications 1 - 7 of 7.

Publications using NBP2-45887	Applications	Species
Song K, Hu J, Yang M et Al. Pulsed electromagnetic fields potentiate bone marrow mesenchymal stem cell chondrogenesis by regulating the Wnt/?-catenin signaling pathway J Transl Med 2024-08-07 [PMID: 39107784]
Bai H, Zhang Z, Liu L et al. Activation of adenosine A3 receptor attenuates progression of osteoarthritis through inhibiting the NLRP3/caspase-1/GSDMD induced signalling Journal of cellular and molecular medicine 2022-08-01 [PMID: 35775127] (IHC-P, Rat)	IHC-P	Rat
Dexing Xu, Ruozhu Dai, Hao Chi, Wen Ge, Jingfeng Rong Long Non-Coding RNA MEG8 Suppresses Hypoxia-Induced Excessive Proliferation, Migration and Inflammation of Vascular Smooth Muscle Cells by Regulation of the miR-195-5p/RECK Axis Frontiers in Molecular Biosciences 2021-11-01 [PMID: 34790697]
Bai H, Yuan R, Zhang Z et al. Intra-articular Injection of Baicalein Inhibits Cartilage Catabolism and NLRP3 Inflammasome Signaling in a Posttraumatic OA Model Oxidative medicine and cellular longevity 2021-09-02 [PMID: 34512868] (IF/IHC, Rat)	IF/IHC	Rat
Huang Y, Huang L, Li L et al. MicroRNA-25-3p therapy for intervertebral disc degeneration by targeting the IL-1?/ZIP8/MTF1 signaling pathway with a novel thermo-responsive vector Annals of Translational Medicine 2020-12-14 [PMID: 33313245]
Shang S, Ji X, Zhang L et al. Macrophage ABHD5 suppresses NF-kappa B-dependent matrix metalloproteinase expression and cancer metastasis Cancer Res. 2019-08-22 [PMID: 31439546] (KD, Mouse)	KD	Mouse
Huang W, Ao P, Li J et al. Autophagy protects advanced glycation end product-induced apoptosis and. BioMed Research International. 2017-01-16 [PMID: 28265573] (WB, Rat)	WB	Rat

Images	Ratings	Applications	Species	Date	Details
Enlarge	5 reviewed by: Verified Customer	WB	Rat	01/18/2017	View Summary Application Western Blot Sample Tested Chondrocyte cell lysate Species Rat Lot A001

Array NBP2-45887

• MMP-13 Antibodies
• MMP-13 ELISA Kits
• MMP-13 Lysate
• MMP-13 Proteins and Enzymes
• MMP-13 ELISAs