MITF Antibody (21D1418) - BSA Free

Microphthalmia-associated bHLH-LZ transcription factor (Mitf) is a positively acting transcription factor containing a transcription activation domain and a bHLH-LZ domain that mediates DNA-binding and dimerization. Both the transcription activation and bHLH-LZ domains are highly conserved in the closely related TFE3, TFEB and TFEC transcription factors. Mitf can form heterodimers in vitro with the above transcription factors, but not with other bHLH-LZ factors such as Myc, Max or USF. Mitf is expressed as multiple isoforms, which share common transcription activation and DNA-binding domains, but differ in the amino-terminal region. Mitf is targeted by three kinases: GSK-3beta, Map kinase ERK2 and members of the p90 Rsk family of kinases.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

We have publications tested in 1 confirmed species: Human.

We have publications tested in 2 applications: FLOW, WB.

Showing Publications 1 - 2 of 2.

Publications using NB100-56561	Applications	Species
Lin J. R, Izar B, et al. Highly multiplexed immunofluorescence imaging of human tissues and tumors using t-CyCIF and conventional optical microscopes. Elife 2018-07-11 [PMID: 29993362] (FLOW, Human) Details: Citation using the Alexa Fluor 488 format of this antibody.	FLOW	Human
Lee J, Jung E, Lee J et al. Mechanisms of melanogenesis inhibition by 2,5-dimethyl-4-hydroxy-3(2H)-furanone. Br J Dermatol. 2007-08-01 [PMID: 17650175] (WB) Details: Mitf (IMG-488). WB: B16 cells treated with DMHF, Fig 5.	WB

Array NB100-56561

• MITF Antibodies
• MITF ELISA Kits
• MITF Lysate
• MITF Protein