Mouse myeloma cell line NS0-derived recombinant human MIS/AMH Propeptide Leu19-Gln450 Accession # P03971
Specificity
Detects human MIS/AMH Propeptide in direct ELISAs and Western blots. In direct ELISAs, less than 1% cross-reactivity with mature recombinant human MIS is observed.
Source
N/A
Isotype
IgG
Clonality
Polyclonal
Host
Goat
Gene
AMH
Purity Statement
Antigen Affinity-purified
Innovator's Reward
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Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
12 months from date of receipt, -20 to -70 °C as supplied.
1 month, 2 to 8 °C under sterile conditions after reconstitution.
6 months, -20 to -70 °C under sterile conditions after reconstitution.
Buffer
Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.
Preservative
No Preservative
Concentration
LYOPH
Reconstitution Instructions
Reconstitute at 0.2 mg/mL in sterile PBS.
Notes
This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.
Alternate Names for MIS/AMH Antibody - Propeptide
AMH
MIF
MIS
Muellerian hormone
muellerian-inhibiting factor
muellerian-inhibiting substance
Mullerian hormone
Mullerian inhibiting factor
Mullerian inhibiting substance
Background
MIS, also known as anti-Mullerian Hormone (AMH), belongs to the TGF-beta superfamily. It is synthesized as a 140 kDa homodimeric glycoprotein that undergoes proteolytic cleavage into the bioactive homodimeric 26 kDa carboxy-terminus and the 110 kDa dimeric amino-terminus. After cleavage, the amino-terminal propeptide remains non-covalently associated with the bioactive carboxy-terminal active protein. The amino acid sequence of human and mouse MIS propeptides are 67% identical.
Limitations
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
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