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Melanocortin-3 R/MC3R Antibody

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Western Blot: Melanocortin-3 R/MC3R Antibody [NBP3-10027] - Western blot analysis of Melanocortin-3 R/MC3R in Human ACHN Whole Cell lysates. Antibody dilution at 1ug/ml
Western Blot: Melanocortin-3 R/MC3R Antibody [NBP3-10027] - Western blot analysis of Melanocortin-3 R/MC3R in Human ACHN Whole Cell lysates. Antibody dilution at 1ug/ml

Product Details

Summary
Reactivity Hu, MuSpecies Glossary
Applications WB
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated
Concentration
0.5 mg/ml

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Melanocortin-3 R/MC3R Antibody Summary

Immunogen
The immunogen is a synthetic peptide directed towards the C terminal region of human Melanocortin-3 R/MC3R (NP_063941.3). Peptide sequence PTNPYCICYTAHFNTYLVLIMCNSVIDPLIYAFRSLELRNTFREILCGCN
Clonality
Polyclonal
Host
Rabbit
Gene
MC3R
Purity
Affinity purified
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Applications/Dilutions

Dilutions
  • Western Blot 1.0 ug/ml
Theoretical MW
35 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS, 2% Sucrose
Preservative
0.09% Sodium Azide
Concentration
0.5 mg/ml
Purity
Affinity purified

Alternate Names for Melanocortin-3 R/MC3R Antibody

  • BMIQ9
  • MC3
  • MC3R
  • MC3-R
  • melanocortin 3 receptor
  • melanocortin receptor 3
  • Melanocortin-3 R
  • Melanocortin3R
  • Melanocortin-3R
  • OB20
  • Obesity quantitative trait locus
  • OQTL

Background

Melanocortins are ligands for a subgroup of GPCRs positively coupled to Adenylate cylcases, termed as melanocortin receptors (MC1R, MC2R, MC3R, MC4R amd MC5R). These receptors are widely expressed at varied density throughout the body. The MC3R has been widely implicated in inflammation and is also implicated in a role in obesity and metabolism. MC3R KO mice exhibit reduced linear growth and lean mass and are hyperleptinemic and hyperinsulinemic.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol MC3R