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Melanocortin-3 R/MC3R Antibody (345404) [Janelia Fluor® 669]

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Product Details

Summary
Reactivity MuSpecies Glossary
Applications Flow, CyTOF-ready
Clone
345404
Clonality
Monoclonal
Host
Rat
Conjugate
Janelia Fluor 669

Order Details

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Melanocortin-3 R/MC3R Antibody (345404) [Janelia Fluor® 669] Summary

Immunogen
Y3 rat myeloid cell line transfeced with mouse Melanocortin 3R/MC3R
Specificity
Detects Melanocortin 3R/MC3R in direct ELISAs and Western blots. Stains mouse Melanocortin 3R/MC3R-transfected cells but not irrelevant transfectants.
Isotype
IgG2a
Clonality
Monoclonal
Host
Rat
Gene
MC3R
Purity
Protein A or G purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • CyTOF-ready
  • Flow Cytometry
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Protein A or G purified

Notes



Sold under license from the Howard Hughes Medical Institute, Janelia Research Campus.

Alternate Names for Melanocortin-3 R/MC3R Antibody (345404) [Janelia Fluor® 669]

  • BMIQ9
  • MC3
  • MC3R
  • MC3-R
  • melanocortin 3 receptor
  • melanocortin receptor 3
  • Melanocortin-3 R
  • Melanocortin3R
  • Melanocortin-3R
  • OB20
  • Obesity quantitative trait locus
  • OQTL

Background

Melanocortins are ligands for a subgroup of GPCRs positively coupled to Adenylate cylcases, termed as melanocortin receptors (MC1R, MC2R, MC3R, MC4R amd MC5R). These receptors are widely expressed at varied density throughout the body. The MC3R has been widely implicated in inflammation and is also implicated in a role in obesity and metabolism. MC3R KO mice exhibit reduced linear growth and lean mass and are hyperleptinemic and hyperinsulinemic.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Secondary Antibodies

 

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Bioinformatics

Gene Symbol MC3R