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Latexin Antibody

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Western Blot: Latexin Antibody [NB100-57856] - Staining of Rat Brain lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
Western Blot: Latexin Antibody [NB100-57856] - (0.1ug/ml) staining of Rat Brain lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

Product Details

Summary
Reactivity Hu, Mu, Rt, CaSpecies Glossary
Applications WB, ELISA, IHC
Clonality
Polyclonal
Host
Goat
Conjugate
Unconjugated
Concentration
0.5 mg/ml

Order Details

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Latexin Antibody Summary

Immunogen
Peptide with sequence C-QYGTKVKHNSRLPKE corresponding to C-Terminus according to NP_064554.2.
Epitope
QYGTKVKHNSRLPKE
Predicted Species
Canine (100%). Backed by our 100% Guarantee.
Isotype
IgG
Clonality
Polyclonal
Host
Goat
Gene
LXN
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Immunohistochemistry 1:200
  • Immunohistochemistry-Paraffin 1:200
  • Peptide ELISA Detection limit 1:128000
  • Western Blot 1 - 3 ug/ml
Application Notes
WB: Approx. 30 kDa band observed in lysates of human brain (cerebellum), mouse brain and rat brain (calculated MW of 25.8 kDa band according to NP_064554.2). IHC-P successful usage for mouse bones is reported in scientific literature (PMID: 19059214).
Control
Latexin Overexpression Lysate
Publications
Read Publications using
NB100-57856 in the following applications:

Packaging, Storage & Formulations

Storage
Store at -20C. Avoid freeze-thaw cycles.
Buffer
Tris saline (20 mM Tris pH 7.3, 150 mM NaCl), 0.5% BSA
Preservative
0.02% Sodium Azide
Concentration
0.5 mg/ml
Purity
Immunogen affinity purified

Alternate Names for Latexin Antibody

  • ECI
  • ECIMUM
  • Endogenous carboxypeptidase inhibitor
  • Latexin
  • LXN
  • TCI
  • TCIProtein MUM
  • Tissue carboxypeptidase inhibitor

Background

Latexin, a protein possessing inhibitory activity against rat carboxypeptidase A1 (CPA1) and CPA2, is expressed in a neuronal subset in the cerebral cortex and cells in other neural and non-neural tissues of rat. Although latexin also inhibits mast-cell CPA (MCCPA), the expression of latexin in rat mast cells has not previously been confirmed.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for Latexin Antibody (NB100-57856)(2)

We have publications tested in 1 confirmed species: Mouse.

We have publications tested in 1 application: IHC-P.


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IHC-P
(1)
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Mouse
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Product General Protocols

Find general support by application which include: protocols, troubleshooting, illustrated assays, videos and webinars.

Video Protocols

WB Video Protocol

FAQs for Latexin Antibody (NB100-57856) (0)

There are no specific FAQs related to this product. Read our general customer & technical service FAQs.

Control Lysate(s)

Secondary Antibodies

 

Isotype Controls

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Research Areas for Latexin Antibody (NB100-57856)

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Blogs on Latexin.

Chromatin reader domains of DNMT-targeting protein, UHRF1, are responsible for cancerous DNA hypermethylation
By Jamshed Arslan, Pharm. D., PhD. DNA methylation represses transcription of many genes, including tumor suppressor genes. A protein called UHRF1 recruits DNA methyltransferases (DNMTs) to establish and maintain DNA...  Read full blog post.

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Bioinformatics

Gene Symbol LXN
Entrez
Uniprot