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Latexin Antibody (OTI1E10) [Janelia Fluor® 635]

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Product Details

Summary
Reactivity Hu, MuSpecies Glossary
Applications WB, Flow, IHC, CyTOF-ready
Clone
OTI1E10
Clonality
Monoclonal
Host
Mouse
Conjugate
Janelia Fluor 635

Order Details

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Latexin Antibody (OTI1E10) [Janelia Fluor® 635] Summary

Immunogen
Full length human recombinant protein of human LXN(NP_064554) produced in HEK293T cell.
Isotype
IgG1
Clonality
Monoclonal
Host
Mouse
Gene
LXN
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • CyTOF-ready
  • Flow Cytometry
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin
  • Western Blot
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Reactivity Notes

Please note that this antibody is reactive to Mouse and derived from the same host, Mouse. Mouse-On-Mouse blocking reagent may be needed for IHC and ICC experiments to reduce high background signal. You can find these reagents under catalog numbers PK-2200-NB and MP-2400-NB. Please contact Technical Support if you have any questions.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Immunogen affinity purified

Notes



Sold under license from the Howard Hughes Medical Institute, Janelia Research Campus.

Alternate Names for Latexin Antibody (OTI1E10) [Janelia Fluor® 635]

  • ECI
  • ECIMUM
  • Endogenous carboxypeptidase inhibitor
  • Latexin
  • LXN
  • TCI
  • TCIProtein MUM
  • Tissue carboxypeptidase inhibitor

Background

Latexin, a protein possessing inhibitory activity against rat carboxypeptidase A1 (CPA1) and CPA2, is expressed in a neuronal subset in the cerebral cortex and cells in other neural and non-neural tissues of rat. Although latexin also inhibits mast-cell CPA (MCCPA), the expression of latexin in rat mast cells has not previously been confirmed.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Video Protocols

WB Video Protocol

FAQs for Latexin Antibody (NBP2-72069JF635) (0)

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Secondary Antibodies

 

Isotype Controls

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Research Areas for Latexin Antibody (NBP2-72069JF635)

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Chromatin reader domains of DNMT-targeting protein, UHRF1, are responsible for cancerous DNA hypermethylation
By Jamshed Arslan, Pharm. D., PhD. DNA methylation represses transcription of many genes, including tumor suppressor genes. A protein called UHRF1 recruits DNA methyltransferases (DNMTs) to establish and maintain DNA...  Read full blog post.

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Bioinformatics

Gene Symbol LXN