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L3MBTL4 Antibody

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Immunocytochemistry/ Immunofluorescence: L3MBTL4 Antibody [NBP2-56598] - Staining of human cell line SH-SY5Y shows localization to nucleoplasm & vesicles.

Product Details

Summary
Reactivity HuSpecies Glossary
Applications ICC/IF
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated

Order Details

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L3MBTL4 Antibody Summary

Immunogen
This antibody was developed against a recombinant protein corresponding to the following amino acid sequence: YWCDVNSPYVQPVGWCQENGRTLIAPQGYPNPENFSWTEYLEATQTNAVPAKVFKMRLPHGFL
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
L3MBTL4
Purity
Affinity purified
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Applications/Dilutions

Dilutions
  • Immunocytochemistry/ Immunofluorescence 0.25-2 ug/ml
Application Notes
Immunocytochemistry/Immunofluorescence Fixation Permeabilization: Use PFA/Triton X-100.
Control Peptide
L3MBTL4 Recombinant Protein Antigen (NBP2-56598PEP)

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.2) and 40% Glycerol
Preservative
0.02% Sodium Azide
Purity
Affinity purified

Alternate Names for L3MBTL4 Antibody

  • FLJ35936
  • H-l(3)mbt-like protein 4
  • HsT1031
  • l(3)mbt-like 4 (Drosophila)
  • L(3)mbt-like protein 4
  • lethal(3)malignant brain tumor-like protein 4

Background

L3MBTL4, also known as Lethal(3)malignant brain tumor-like protein 4, has a 623 amino acid isoform that is 71 kDa and a short 534 amino acid that is 61 kDa, nucleus located; belongs to Putative Polycomb group (PcG), and maintains the transcriptionally repressive state of genes, probably via a modification of chromatin, rendering it heritably changed in its expressibility. There has been research revolving around the L3MBTL4 protein involvement in breast cancer. This protein is involved in transcription, DNA-dependent; regulation of transcription, DNA-dependent; and chromatin modification pathways.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Video Protocols

ICC/IF Video Protocol

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Secondary Antibodies

 

Isotype Controls

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Bioinformatics

Gene Symbol L3MBTL4