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KLRA1 Antibody - BSA Free

Images

 
Western Blot: KLRA1 Antibody [NBP1-77343] - Mouse spleen tissue lysate with KLRA1 antibody at (A) 1 ug/ml and (B) 2 ug/ml.
Immunocytochemistry/ Immunofluorescence: KLRA1 Antibody - BSA Free [NBP1-77343] - Immunocytochemistry of KLRA1 in 293 cells with KLRA1 antibody at 4 u/mL.
Immunocytochemistry/ Immunofluorescence: KLRA1 Antibody - BSA Free [NBP1-77343] - Immunofluorescence of KLRA1 in 293 cells with KLRA1 antibody at 20 ug/mL.

Product Details

Summary
Reactivity Hu, Mu, RtSpecies Glossary
Applications WB, ELISA, ICC/IF
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated
Format
BSA Free
Concentration
1 mg/ml

Order Details

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KLRA1 Antibody - BSA Free Summary

Immunogen
Antibody was raised against a 13 amino acid synthetic peptide near the center of human KLRA1. The immunogen is located within amino acids 140 - 190 of KLRA1. Amino Acid Squence: CYYFTMQKKDWKG
Specificity
At least three isoforms of KLRA1 are known to exist; this antibody recognizes only the long isoform.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
KLRA1P
Purity
Peptide affinity purified
Innovator's Reward
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Applications/Dilutions

Dilutions
  • ELISA 1:100-1:2000
  • Immunocytochemistry/ Immunofluorescence 4-20 ug/ml
  • Western Blot 1-2 ug/ml
Control Peptide
KLRA1 Peptide (NBP1-77343PEP)

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS
Preservative
0.02% Sodium Azide
Concentration
1 mg/ml
Purity
Peptide affinity purified

Alternate Names for KLRA1 Antibody - BSA Free

  • killer cell lectin-like receptor subfamily A pseudogene 1
  • KLRA#
  • KLRA1
  • Ly49
  • LY49L
  • Ly-49L
  • MGC126520
  • MGC126522

Background

KLRA1 (also known as Ly49L) is a member of the LY49 family of receptors in Natural Killer (NK) cells that bind to major histocompatibility complex (MHC) class 1. These proteins are classified as either activating or inhibitory receptors based on whether they possess an immunoreceptor tyrosine-based inhibitory motif (ITIM) in their cytoplasmic region (for inhibitory receptors), or an immunoreceptor tyrosine-based activation motif (ITAM) that transmits activating signals resulting in phosphorylation of several substrates. KLRA1 is thought to be an activating receptor, inducing DAP12 phosphorylation in response to antibody-mediated cross-linking of KLRA1 on NK cells. At least three isoforms of KLRA1 are known to exist; this antibody recognizes only the long isoform.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Video Protocols

WB Video Protocol
ICC/IF Video Protocol

FAQs for KLRA1 Antibody (NBP1-77343) (0)

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Secondary Antibodies

 

Isotype Controls

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Bioinformatics

Gene Symbol KLRA1P
Uniprot