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KIR2DL3/CD158b2 Antibody (180701) [Phycoerythrin]

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Human peripheral blood mononuclear cells (PBMCs) were stained with Mouse Anti-Human KIR2DL3/CD158b2 PE-conjugated Monoclonal Antibody (Catalog # FAB2014P) and Mouse Anti-Human NCAM-1/CD56 APC-conjugated Monoclonal ...read more

Product Details

Summary
Reactivity HuSpecies Glossary
Applications Flow
Clone
180701
Clonality
Monoclonal
Host
Mouse
Conjugate
Phycoerythrin

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KIR2DL3/CD158b2 Antibody (180701) [Phycoerythrin] Summary

Immunogen
BaF3 mouse pro-B cell line transfected with human KIR2DL3/CD158b2
Accession # P43628
Specificity
Detects human KIR2DL3/CD158b2. Stains BaF3 cells transfected with human KIR2DL3 in flow cytometry. Does not stain BaF3 cells transfected with KIR2DL1, 2DL2, 2DL4, 2DL5, 2DS1, 2DS2, 2DS4, 3DL1, 3DL2, or 3DS1.
Source
N/A
Isotype
IgG2a
Clonality
Monoclonal
Host
Mouse
Gene
KIR2DL3
Purity Statement
Protein A or G purified from hybridoma culture supernatant
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Flow Cytometry 10 uL/10^6 cells
Publications
Read Publications using
FAB2014P in the following applications:

Packaging, Storage & Formulations

Storage
Protect from light. Do not freeze.
  • 12 months from date of receipt, 2 to 8 °C as supplied.
Buffer
Supplied in a saline solution containing BSA and Sodium Azide.
Preservative
Sodium Azide

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for KIR2DL3/CD158b2 Antibody (180701) [Phycoerythrin]

  • CD158 antigen-like family member B2
  • CD158b2 antigen
  • CD158b2
  • CD158B2CD158b
  • cl-6
  • killer cell immunoglobulin-like receptor 2DL3
  • killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 3
  • Killer inhibitory receptor cl 2-3
  • KIR-023GB
  • KIR2DL3
  • KIRCL23
  • KIR-K7b
  • KIR-K7c
  • MGC129943
  • MHC class I NK cell receptor
  • natural killer associated transcript 2
  • natural killer cell inhibitory receptor KIR2DL3
  • Natural killer-associated transcript 2
  • NKAT
  • NKAT2
  • NKAT-2
  • NKAT2A
  • nkat2b
  • NKAT2GL183
  • NK-receptor
  • p58 natural killer cell receptor clone CL-6
  • p58 NK receptor CL-6
  • p58
  • p58.2 MHC class-I specific NK receptor
  • p58.2 MHC class-I-specific NK receptor

Background

KIR2DL3 is one of several immunoglobulin-like receptors expressed on NK and T cells that bind MHC class I molecules and regulate killer cell activity. KIR2DL3 interacts specifically with HLA-Cw3.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for KIR2DL3/CD158b2 Antibody (FAB2014P)(10)

We have publications tested in 1 confirmed species: Human.

We have publications tested in 1 application: Flow Cytometry.


Filter By Application
Flow Cytometry
(9)
All Applications
Filter By Species
Human
(9)
All Species
Showing Publications 1 - 10 of 10.
Publications using FAB2014P Applications Species
Benjamin H. Goldenson, Huang Zhu, YunZu Michele Wang, Naveen Heragu, Davide Bernareggi, Alessa Ruiz-Cisneros et al. Umbilical Cord Blood and iPSC-Derived Natural Killer Cells Demonstrate Key Differences in Cytotoxic Activity and KIR Profiles Frontiers in Immunology 2020-10-15 [PMID: 33178188]
Samarani S, Sagala P, Jantchou P, Grimard G, Faure C, Deslandres C, Amre D, Ahmad A Phenotypic and Functional Changes in Peripheral Blood Natural Killer Cells in Crohn Disease Patients. Mediators Inflamm, 2020-02-19;2020(0):6401969. 2020-02-19 [PMID: 32148442] (Flow Cytometry, Human) Flow Cytometry Human
I Lisovsky, S Kant, A Tremblay-M, G Isitman, Z Kiani, FP Dupuy, L Gilbert, J Bruneau, NH Shoukry, B Lebouché, NF Bernard Differential contribution of education through KIR2DL1, KIR2DL3, and KIR3DL1 to antibody-dependent (AD) NK cell activation and ADCC J. Leukoc. Biol., 2019-01-30;0(0):. 2019-01-30 [PMID: 30698860] (Flow Cytometry, Human) Flow Cytometry Human
Grzegorz Terszowski Human Cytomegalovirus Infection Enhances NK Cell Activity In Vitro Transplant Direct, 2016-06-17;2(7):e89. 2016-06-17 [PMID: 27830183] (Flow Cytometry, Human) Flow Cytometry Human
Li W, Jiang Y, Wang X, Jin J, Qi Y, Chi X, Zhang H, Feng X, Niu J Natural Killer p46 Controls Hepatitis B Virus Replication and Modulates Liver Inflammation. PLoS ONE, 2015-08-20;10(8):e0135874. 2015-08-20 [PMID: 26291078] (Flow Cytometry, Human) Flow Cytometry Human
Holmes T, Wilson E, Black E, Benest A, Vaz C, Tan B, Tanavde V, Cook G Licensed human natural killer cells aid dendritic cell maturation via TNFSF14/LIGHT. Proc Natl Acad Sci U S A, 2014-12-15;111(52):E5688-96. 2014-12-15 [PMID: 25512551] (Flow Cytometry, Human) Flow Cytometry Human
Hu X, Jiang Y, Li X, Gao Y, Guo X, Chi X, Yan H, Feng J, Zhong J, Sun B, Shao X, Xiao W, Pan Y, Niu J Long-term effect on natural killer cells by interferon-alpha therapy on the outcomes of HCV infection. J Interferon Cytokine Res, 2013-12-24;34(5):366-75. 2013-12-24 [PMID: 24367931] (Flow Cytometry, Human) Flow Cytometry Human
Charoudeh H, Terszowski G, Czaja K, Gonzalez A, Schmitter K, Stern M Modulation of the natural killer cell KIR repertoire by cytomegalovirus infection. Eur J Immunol, 2012-12-12;43(2):480-7. 2012-12-12 [PMID: 23161492] (Flow Cytometry, Human) Flow Cytometry Human
Yu J, Mitsui T, Wei M, Mao H, Butchar JP, Shah MV, Zhang J, Mishra A, Alvarez-Breckenridge C, Liu X, Liu S, Yokohama A, Trotta R, Marcucci G, Benson DM, Loughran TP, Tridandapani S, Caligiuri MA NKp46 identifies an NKT cell subset susceptible to leukemic transformation in mouse and human. J. Clin. Invest., 2011-04-01;121(4):1456-70. 2011-04-01 [PMID: 21364281] (Flow Cytometry, Human) Flow Cytometry Human
Alici E, Sutlu T, Bjorkstrand B, Gilljam M, Stellan B, Nahi H, Quezada HC, Gahrton G, Ljunggren HG, Dilber MS Autologous antitumor activity by NK cells expanded from myeloma patients using GMP-compliant components. Blood, 2008-01-11;111(6):3155-62. 2008-01-11 [PMID: 18192509] (Flow Cytometry, Human) Flow Cytometry Human

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Bioinformatics

Gene Symbol KIR2DL3
Uniprot